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文献和实验免疫球蛋白 A(immunoglobulin A, IgA)
在正常人血清中的含量仅次于IgG,占血清免疫球蛋白含量的10~20%。从结构来看,IgA有单体、双体、三体及多聚体之分。按其免疫功能又分为血清型及分泌型两种。血清型IgA存在于血清中,其含量占总IgA的85%左右。血清型IgA虽有IgG和IgM的某些功能,但在血清中并不显示重要的免疫功能。分泌型IgA存在于分泌液中,如唾液、泪液、初乳、鼻和支气管分泌液、胃肠液、尿液、汗液等。分泌型IgA是机体粘膜局部抗感染免疫的主要抗体。故又称粘膜局部抗体。IgA不能通过胎盘。新生
35 Expression of Antibody Fab Fragments and Whole Immunoglobulin in Mammalian Cells
(1 -7 ). Production of selected Abs in sufficient quantity for further evaluation often requires the transfer of their coding sequences to vectors specfiically designed for expression in eukaryotic cells. For Fab and/or immunoglobulin G (IgG) expression, these systems
Purification and Characterization of Human Serum and Secretory IgA1 and IgA2 Using Jacalin
Human immunoglobulin A (IgA) is found in serum and secretions in several different forms (1 ), Serum IgA is produced by the bone marrow and is pre-dominately monomeric (M r = 160 kDa
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