相关产品推荐更多 >

Rabbit anti-SERPINI2 Polyclonal Antibody【兔抗SERPINI2多克隆抗体】- abs151313
¥1600
Mouse anti-MMP2 Monoclonal Antibody【鼠抗MMP2单克隆抗体】-abs112854
¥1500
Rabbit anti-KCNA2B Polyclonal Antibody【兔抗KCNA2B多克隆抗体】- abs121777
¥2300
Rabbit anti-PTK6 Polyclonal Antibody【兔抗PTK6多克隆抗体】-abs117941
¥1500
Rabbit anti-LHFPL2 Polyclonal Antibody【兔抗LHFPL2多克隆抗体】- abs151452
¥1600
万千商家帮你免费找货
0 人在求购买到急需产品
相关阅读
源叶生物 十万种现货试剂速发,品质稳、品类全,实验不再等!Takara 秋促来袭,提取+反转录+定量套装仅 1200 元abinScience 体内级抗体 全年锁价 低至 ¥1200阿拉丁 22万+ 科研级产品现货速发,品质严控、科研无忧- 详细信息
- 文献和实验
- 技术资料
- 供应商:
BD Pharmingen
- 靶点:
HLA-DR
- 级别:
RUO
- 克隆性:
单克隆
- 抗原来源:
Human
- 抗体英文名:
HLA-DR Antibody
- 抗体名:
HLA-DR
- 标记物:
BV605
- 宿主:
Mouse
- 适应物种:
Human
- 免疫原:
Human lymphoblastoid B-cell line RPMI 8866
- 亚型:
Mouse IgG2a, κ
- 形态:
液体
- 应用范围:
Flow Cytometry (FCM)
- 保存条件:
2-8℃避光保存
- 规格:
25 Tests
产品概述
Hu HLA-DR BV605 L243 25Tst 为 BD Pharmingen 品牌流式抗体,货号 569307,靶向 HLA-DR,荧光标记 BV605,克隆 L243 (RUO),规格 25 Tests。适用于 Flow cytometry (Routinely Tested) 检测,仅供科研使用(RUO)。
靶点与抗体说明
The L243 monoclonal antibody specifically binds to HLA-DR, a major histocompatibility complex (MHC) class II antigen. HLA-DR antigens are encoded by genes within the Human Leukocyte Antigen (HLA) Complex located on chromosome 6. HLA-DR is a transmembrane heterodimeric glycoprotein composed of an α chain (36 kDa) and a β subunit (27 kDa) expressed primarily on antigen presenting cells including B cells, dendritic cells, monocytes, macrophages, Langerhans cells, and thymic epithelial cells. HLA-DR is also expressed on activated T cells. This molecule plays a major role in mediating cellular interactions during antigen presentation to CD4-positive T cells.
核心参数
| 货号 | 569307 |
| 品牌 | BD Pharmingen |
| 克隆号 | 克隆 L243 (RUO) |
| 宿主 | Mouse |
| 同种型 | Mouse IgG2a, κ |
| 荧光标记 | BV605 |
| 抗原 / 靶点 | HLA-DR |
| 反应种属 | Human |
| 验证应用 | Flow cytometry (Routinely Tested) |
| 推荐用量 | 5 µl/test |
| 免疫原 | Human lymphoblastoid B-cell line RPMI 8866 |
| 规格 | 25 Tests |
| 存储缓冲液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
荧光染料信息
BV605 The BD Horizon Brilliant Violet™ 605 (BV605) dye is part of the BD Horizon Brilliant Violet™ family of dyes. This tandem fluorochrome is comprised of a BV421 donor with an excitation maximum (Ex Max) of 407-nm and an acceptor dye with an emission maximum (Em Max) at 605-nm. BV605, driven by BD innovation, is designed to be excited by the violet laser (405-nm) and detected using an optical filter centered near 610-nm (e.g., a 610/20-nm bandpass filter). The acceptor dye can be excited by the yellow-green (561-nm) laser resulting in cross-laser excitation and fluorescence spillover. Please ensure that your instrument’s configurations (lasers and optical filters) are appropriate for this dye. 格式:BV605最多激发源:407 nm最多发射源:605 nm
保存与运输
建议 2-8℃ 避光保存,请勿冷冻,避免反复冻融。 存储缓冲液:Aqueous buffered solution containing ≤0.09% sodium azide.
参考文献
Autissier P, Soulas C, Burdo TH, Williams KC. Evaluation of a 12-color flow cytometry panel to study lymphocyte, monocyte, and dendritic cell subsets in humans.. Cytometry A. 2010; 77(5):410-9. (Clone-specific: Flow cytometry). Brodsky FM. A matrix approach to human class II histocompatibility antigens: reactions of four monoclonal antibodies with the products of nine haplotypes.. Immunogenetics. 1984; 19(3):179-94. (Clone-specific: Blocking, Immunoprecipitation, Radioimmunoassay). Charles N, Hardwick D, Daugas E, Illei GG, Rivera J. Basophils and the T helper 2 environment can promote the development of lupus nephritis.. Nat Med. 2010; 16(6):701-7. (Clone-specific: Flow cytometry). Engleman EG, Warnke R, Fox RI, Dilley J, Benike CJ, Levy R. Studies of a human T lymphocyte antigen recognized by a monoclonal antibody.. Proc Natl Acad Sci USA. 1981; 78(3):1791-5. (Clone-specific: Immunohistochemistry). Fujita H, Nograles KE, Kikuchi T, Gonzalez J, Carucci JA, Krueger JG. Human Langerhans cells induce distinct IL-22-producing CD4+ T cells lacking IL-17 production.. Proc Natl Acad Sci U S A. 2009; 106(51):21795-800. (Clone-specific: Flow cytometry). Harper D, Gollackner B, Xu Y, et al. In vitro and in vivo investigation of a novel monoclonal antibody to plasma cells (W5 mAb).. Xenotransplantation. 2004; 11(1):78-90. (Clone-specific: Immunoprecipitation). Lampson LA, Levy R. Two populations of Ia-like molecules on a human B cell line.. J Immunol. 1980; 125(1):293-9. (Immunogen: Blocking, Immunoprecipitation, Radioimmunoassay). Ren Z, Wang J, Zhu W, et al. Spontaneous transformation of adult mesenchymal stem cells from cynomolgus macaques in vitro.. Exp Cell Res. 2011; 317(20):2950-7. (Clone-specific: Flow cytometry). Stumptner-Cuvelette P, Morchoisne S, Dugast M, et al. HIV-1 Nef impairs MHC class II antigen presentation and surface expression.. Proc Natl Acad Sci U S A. 2001; 98(21):12144-9. (Clone-specific: Flow cytometry). Tomkinson BE, Wagner DK, Nelson DL, Sullivan JL. Activated lymphocytes during acute Epstein-Barr virus infection.. J Immunol. 1987; 139(11):3802-7. (Clone-specific: Flow cytometry). Wang RF, Wang X, Atwood AC, Topalian SL, Rosenberg SA. Cloning genes encoding MHC class II-restricted antigens: mutated CDC27 as a tumor antigen.. Science. 1999; 284(5418):1351-4. (Clone-specific: Blocking). Weisgrau KL, Vosler LJ, Pomplun NL, et al. Neutrophil progenitor populations of rhesus macaques.. J Leukoc Biol. 2019; 105(1):113-121. (Clone-specific: Cel
风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验3 H-TdR渗入增加)。这是T细胞识别非T细胞单核-巨噬细胞、B细胞、Null细胞上的自身HLA-DR分子而发生的反应,即在无非已抗原的参加下,只通过识别自身万分就可诱导产生T H 、T K 功能。其反应过程中,首先OKT 4 + 的T H 与单核-巨噬细胞上的DR分子相互反应,一方面导致T H 活化,细胞膜上出现白细胞介素-1(IL-1)受体,另一方面也导致单核-巨噬细胞释放
祝贺〖雅裕睿安〗成为Signalway Antibody(SAB)独家
【 C 】 抗体组合套装优惠活动 活动日期:即日起,至 2011 年 12 月 31 日 促销代码: 201106SAB 从 SAB 产品目录中任选 4 个 25ul 规格抗体组成的套装仅售¥ 1700 。 8 个 25ul 规格抗体组成的套装售价¥ 3200 。 16 支 25ul 规格抗体
cells and peptide sequences to home to specific tissues after intravenous injection23-25. Several receptors to angiogenic factors have been identified26-28 and genomic analysis of endothelial cells isolated from tumours has provided angiogenic
技术资料暂无技术资料 索取技术资料





