Hu HLA-DR BV605 L243 25Tst产品图

Hu HLA-DR BV605 L243 25Tst

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  • ¥3058.0¥88特惠体验价
  • BD
  • 美国
  • 569307
  • 2026年10月23日
  • Flow Cytometry (FCM)
  • Mouse
  • Human
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  • 促销:近效期抗体
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 供应商:

      BD Pharmingen

    • 靶点:

      HLA-DR

    • 级别:

      RUO

    • 克隆性:

      单克隆

    • 抗原来源:

      Human

    • 抗体英文名:

      HLA-DR Antibody

    • 抗体名:

      HLA-DR

    • 标记物:

      BV605

    • 宿主:

      Mouse

    • 适应物种:

      Human

    • 免疫原:

      Human lymphoblastoid B-cell line RPMI 8866

    • 亚型:

      Mouse IgG2a, κ

    • 形态:

      液体

    • 应用范围:

      Flow Cytometry (FCM)

    • 保存条件:

      2-8℃避光保存

    • 规格:

      25 Tests

    产品概述

    Hu HLA-DR BV605 L243 25Tst 为 BD Pharmingen 品牌流式抗体,货号 569307,靶向 HLA-DR,荧光标记 BV605,克隆 L243 (RUO),规格 25 Tests。适用于 Flow cytometry (Routinely Tested) 检测,仅供科研使用(RUO)。

    靶点与抗体说明

    The L243 monoclonal antibody specifically binds to HLA-DR, a major histocompatibility complex (MHC) class II antigen. HLA-DR antigens are encoded by genes within the Human Leukocyte Antigen (HLA) Complex located on chromosome 6. HLA-DR is a transmembrane heterodimeric glycoprotein composed of an α chain (36 kDa) and a β subunit (27 kDa) expressed primarily on antigen presenting cells including B cells, dendritic cells, monocytes, macrophages, Langerhans cells, and thymic epithelial cells. HLA-DR is also expressed on activated T cells. This molecule plays a major role in mediating cellular interactions during antigen presentation to CD4-positive T cells.

    核心参数

    货号 569307
    品牌 BD Pharmingen
    克隆号 克隆 L243 (RUO)
    宿主 Mouse
    同种型 Mouse IgG2a, κ
    荧光标记 BV605
    抗原 / 靶点 HLA-DR
    反应种属 Human
    验证应用 Flow cytometry (Routinely Tested)
    推荐用量 5 µl/test
    免疫原 Human lymphoblastoid B-cell line RPMI 8866
    规格 25 Tests
    存储缓冲液 Aqueous buffered solution containing ≤0.09% sodium azide.

    荧光染料信息

    BV605 The BD Horizon Brilliant Violet™ 605 (BV605) dye is part of the BD Horizon Brilliant Violet™ family of dyes. This tandem fluorochrome is comprised of a BV421 donor with an excitation maximum (Ex Max) of 407-nm and an acceptor dye with an emission maximum (Em Max) at 605-nm. BV605, driven by BD innovation, is designed to be excited by the violet laser (405-nm) and detected using an optical filter centered near 610-nm (e.g., a 610/20-nm bandpass filter). The acceptor dye can be excited by the yellow-green (561-nm) laser resulting in cross-laser excitation and fluorescence spillover. Please ensure that your instrument’s configurations (lasers and optical filters) are appropriate for this dye. 格式:BV605最多激发源:407 nm最多发射源:605 nm

    保存与运输

    建议 2-8℃ 避光保存,请勿冷冻,避免反复冻融。 存储缓冲液:Aqueous buffered solution containing ≤0.09% sodium azide.

    参考文献

    Autissier P, Soulas C, Burdo TH, Williams KC. Evaluation of a 12-color flow cytometry panel to study lymphocyte, monocyte, and dendritic cell subsets in humans.. Cytometry A. 2010; 77(5):410-9. (Clone-specific: Flow cytometry). Brodsky FM. A matrix approach to human class II histocompatibility antigens: reactions of four monoclonal antibodies with the products of nine haplotypes.. Immunogenetics. 1984; 19(3):179-94. (Clone-specific: Blocking, Immunoprecipitation, Radioimmunoassay). Charles N, Hardwick D, Daugas E, Illei GG, Rivera J. Basophils and the T helper 2 environment can promote the development of lupus nephritis.. Nat Med. 2010; 16(6):701-7. (Clone-specific: Flow cytometry). Engleman EG, Warnke R, Fox RI, Dilley J, Benike CJ, Levy R. Studies of a human T lymphocyte antigen recognized by a monoclonal antibody.. Proc Natl Acad Sci USA. 1981; 78(3):1791-5. (Clone-specific: Immunohistochemistry). Fujita H, Nograles KE, Kikuchi T, Gonzalez J, Carucci JA, Krueger JG. Human Langerhans cells induce distinct IL-22-producing CD4+ T cells lacking IL-17 production.. Proc Natl Acad Sci U S A. 2009; 106(51):21795-800. (Clone-specific: Flow cytometry). Harper D, Gollackner B, Xu Y, et al. In vitro and in vivo investigation of a novel monoclonal antibody to plasma cells (W5 mAb).. Xenotransplantation. 2004; 11(1):78-90. (Clone-specific: Immunoprecipitation). Lampson LA, Levy R. Two populations of Ia-like molecules on a human B cell line.. J Immunol. 1980; 125(1):293-9. (Immunogen: Blocking, Immunoprecipitation, Radioimmunoassay). Ren Z, Wang J, Zhu W, et al. Spontaneous transformation of adult mesenchymal stem cells from cynomolgus macaques in vitro.. Exp Cell Res. 2011; 317(20):2950-7. (Clone-specific: Flow cytometry). Stumptner-Cuvelette P, Morchoisne S, Dugast M, et al. HIV-1 Nef impairs MHC class II antigen presentation and surface expression.. Proc Natl Acad Sci U S A. 2001; 98(21):12144-9. (Clone-specific: Flow cytometry). Tomkinson BE, Wagner DK, Nelson DL, Sullivan JL. Activated lymphocytes during acute Epstein-Barr virus infection.. J Immunol. 1987; 139(11):3802-7. (Clone-specific: Flow cytometry). Wang RF, Wang X, Atwood AC, Topalian SL, Rosenberg SA. Cloning genes encoding MHC class II-restricted antigens: mutated CDC27 as a tumor antigen.. Science. 1999; 284(5418):1351-4. (Clone-specific: Blocking). Weisgrau KL, Vosler LJ, Pomplun NL, et al. Neutrophil progenitor populations of rhesus macaques.. J Leukoc Biol. 2019; 105(1):113-121. (Clone-specific: Cel

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    Hu HLA-DR BV605 L243 25Tst
    ¥3058.0¥88特惠体验价