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Recombinant Human Glycogen Pho

sphorylase
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  • ¥987 - 2457
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  • 上海
  • abs44074343
  • 2025年08月28日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 保存条件

      GPBB although stable at 10°C for 7 days, should be stored below -18°C. Please prevent freeze-thaw cycles.

    • 保质期

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    • 英文名

      Recombinant Human Glycogen Phosphorylase

    • 库存

      999

    • 供应商

      Absin

    • 规格

      20ug/5ug

    规格:20ug产品价格:¥2457.0
    规格:5ug产品价格:¥987.0

    产品名:

    Recombinant Human Glycogen Phosphorylase

    品牌:

    Absin

    货号:

    abs44074343

    保持条件:

    GPBB although stable at 10°C for 7 days, should be stored below -18°C. Please prevent freeze-thaw cycles.

    浓度:

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    免疫原:

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    抗原名称:

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    应用:

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    使用方法:

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    产品描述:

        Glycogen phosphorylase is one of the phosphorylaseenzymes(EC2.4.1.1). It breaks up glycogeninto glucosesubunits. Glycogenis left with one less glucosemolecule, and the free glucosemolecule is in the form of glucose-1-phosphate. In order to be used for metabolism, it must be converted to glucose-6-phosphateby the enzyme phosphoglucomutase.
    Glycogen phosphorylase can only act on linearchainsof glycogen(a 1-4 glycosidic linkage). Its work will immediately come to a halt four residues away from a 1-6 branch(which are exceedingly common in glycogen). In these situations, a debranching enzymeis necessary, which will straighten out the chain in that area. Additionally, an alpha 1-6 glucosidaseenzymeis required to break the remaining 1-6 residue that remains in the new linear chain. After all this is done, glycogen phosphorylase can continue.
    An insulinstimulated enzyme known as phosphoprotein phosphatase(PP-1) inactivates glycogen phosphorylase to prevent glycogen break up.
    GPBB - a sensitive marker for the AMI diagnosis within 4 hours after the onset of chest pain. It has also been shown that GPBB is increased in a considerable proportion of AMI patients within 2-3 hours from chest pain onset. GPBB is increased early in patients with unstable angina. GPBB can also be a sensitive marker for the detection of peri-operative myocardial ischaemia and infarction in patients undergoing coronary artery bypass grafting.
     
        Glycogen Phosphorylase Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain. The Human GPBB mature chain: 2 - 843 aa; that is a total of 842 aa having a molecular mass of 96695.96 Dalton. The theoretical pI is 6.40.
        The GPBB is purified by proprietary chromatographic techniques.

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