- ￥480 - 1600
- Solarbio|ActivAb
- 北京
- K116504P
- 2025年08月22日
- IHC
- Rabbit
- Human;Mouse;Rat
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
A synthetic peptide of human NLRP3
- 亚型：
IgG
- 保存条件：
Store at -20℃. Avoid freeze / thaw cycles.
- 克隆性：
Polyclonal Antibody
- 标记物：
Biotin，Cy3，Cy3.5，Cy5，Cy5.5，Cy7，FITC，HRP，RBITC，Solar Fluor 350，Solar Fluor 405，Solar Fluor 488，Solar Fluor 532，Solar Fluor 555，Solar Fluor 568，Solar Fluor 594，Solar Fluor 633，Solar Fluor 640，Solar Fluor 647，Solar Fluor 660，Solar Fluor 680，Solar Fluor 750
- 适应物种：
Human;Mouse;Rat
- 抗原来源：
A synthetic peptide of human NLRP3
- 目录编号：
114548
- 级别：
实验级别
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 宿主：
Rabbit
- 应用范围：
IHC
- 浓度：
IHC 1:50-200.
- 靶点：
NLRP3
- 抗体英文名：
Anti-NLRP3 Polyclonal Antibody
- 抗体名：
细胞凋亡诱导蛋白NALP3抗体
- 规格：
50ul/20ul/100ul
| 规格： | 50ul | 产品价格： | ￥960.0 |
|---|---|---|---|
| 规格： | 20ul | 产品价格： | ￥480.0 |
| 规格： | 100ul | 产品价格： | ￥1600.0 |
| 基本信息 | |
| 英文名称 | Anti-NLRP3 Polyclonal Antibody |
| 中文名称 | 细胞凋亡诱导蛋白NALP3抗体 |
| 宿主 | Rabbit |
| 克隆类型 | Polyclonal Antibody |
| 亚型 | IgG |
| 交叉反应 | Human;Mouse;Rat |
| 预测交叉反应 | Cow(91.7%);Monkey(92.3%) |
| 应用 | IHC |
| 稀释比例 | IHC 1:50-200. |
| 密度 | |
| 靶标 | NLRP3 |
| 别名 | AGTAVPRL; AII/AVP; Angiotensin/vasopressin receptor AII/AVP like; Angiotensin/vasopressin receptor AII/AVP-like; C1orf7; Caterpiller protein 1.1; CIAS 1; CIAS1; CLR1.1; Cold autoinflammatory syndrome 1; Cold autoinflammatory syndrome 1 protein; Cryopyrin; Familial cold autoinflammatory syndrome; FCAS; FCU; LRR and PYD domains-containing protein 3; Muckle-Wells syndrome; MWS; NACHT; NACHT LRR and PYD containing protein 3; NALP 3; NALP3; NALP3_HUMAN; NLR family pyrin domain containing 3; NLRP3; PYPAF 1; PYPAF1; PYRIN containing APAF1 like protein 1; PYRIN-containing APAF1-like protein 1; |
| 背景说明 | This gene encodes a pyrin-like protein containing a pyrin domain， a nucleotide-binding site (NBS) domain， and a leucine-rich repeat (LRR) motif. This protein interacts with the apoptosis-associated speck-like protein PYCARD/ASC， which contains a caspase recruitment domain， and is a member of the NLRP3 inflammasome complex. This complex functions as an upstream activator of NF-kappaB signaling， and it plays a role in the regulation of inflammation， the immune response， and apoptosis. The SARS-CoV 3a protein， a transmembrane pore-forming viroporin， has been shown to activate the NLRP3 inflammasome via the formation of ion channels in macrophages. Mutations in this gene are associated with familial cold autoinflammatory syndrome (FCAS)， Muckle-Wells syndrome (MWS)， chronic infantile neurological cutaneous and articular (CINCA) syndrome， neonatal-onset multisystem inflammatory disease (NOMID)， keratoendotheliitis fugax hereditarian， and deafness， autosomal dominant 34， with or without inflammation. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. Alternative 5‘ UTR structures are suggested by available data; however， insufficient evidence is available to determine if all of the represented 5‘ UTR splice patterns are biologically valid. |
| Swiss Prot | Q96P20 |
| Gene ID | 114548 |
| 亚细胞定位 | Cytoplasm Nucleus |
| 免疫原 | A synthetic peptide of human NLRP3 |
| Public Immunogen Range | 986-1036/1036aa |
| 理论分子量 | 84/106/112/116/118kDa |
| EC | |
| 纯化方法 | Affinity purification |
| 储存液 | PBS with 50% Glycerol， 0.03% Proclin300， 0.5% BSA， pH 7.3. |
| 储存条件 | Store at -20℃. Avoid freeze / thaw cycles. |
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文献和实验Polyclonal Antibody Production
, if desired this is best accomplished by Protein A Affinity Chromatography. 上一篇：make an Antibody against a Peptides 下一篇：Immunization Protocol for Monoclonal Antibody Production
Polyclonal Antibody Production
Polyclonal Antibody Production Very useful for rapid and simple generation of antibodies for western blots, ELISA assays, and immunoprecipitation. Rabbit Immunization Initial Preparation Your antigen
a simple ELISA method to detect human anti-antibody response.
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