- ￥480 - 1600
- Solarbio|ActivAb
- 北京
- K116457P
- 2025年08月22日
- WB
- Rabbit
- Human;Mouse;Rat;Monkey
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Recombinant protein of human PSEN1
- 亚型：
IgG
- 保存条件：
Store at -20℃. Avoid freeze / thaw cycles.
- 克隆性：
Polyclonal Antibody
- 标记物：
Biotin，Cy3，Cy3.5，Cy5，Cy5.5，Cy7，FITC，HRP，RBITC，Solar Fluor 350，Solar Fluor 405，Solar Fluor 488，Solar Fluor 532，Solar Fluor 555，Solar Fluor 568，Solar Fluor 594，Solar Fluor 633，Solar Fluor 640，Solar Fluor 647，Solar Fluor 660，Solar Fluor 680，Solar Fluor 750
- 适应物种：
Human;Mouse;Rat;Monkey
- 抗原来源：
Recombinant protein of human PSEN1
- 目录编号：
5663
- 级别：
实验级别
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 宿主：
Rabbit
- 应用范围：
WB
- 浓度：
WB 1:1000-3000.
- 靶点：
PSEN1
- 抗体英文名：
Anti-PSEN1 Polyclonal Antibody
- 抗体名：
早老素1抗体
- 规格：
50ul/100ul/20ul
| 规格： | 50ul | 产品价格： | ￥960.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1600.0 |
| 规格： | 20ul | 产品价格： | ￥480.0 |
| 基本信息 | |
| 英文名称 | Anti-PSEN1 Polyclonal Antibody |
| 中文名称 | 早老素1抗体 |
| 宿主 | Rabbit |
| 克隆类型 | Polyclonal Antibody |
| 亚型 | IgG |
| 交叉反应 | Human;Mouse;Rat;Monkey |
| 预测交叉反应 | Bovine;Chicken;Zebrafish |
| 应用 | WB |
| 稀释比例 | WB 1:1000-3000. |
| 密度 | |
| 靶标 | PSEN1 |
| 别名 | AD3; Ad3h; FAD; Homo Sapiens Clone CC44 Senilin 1; Presenilin-1 CTF12; Protein S182; PS 1; PS-1; PS1-CTF12; PSEN1; PSN1_HUMAN; PSNL1; S182; |
| 背景说明 | Alzheimer‘s disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1; PSEN2) or in the amyloid precursor protein (APP). These disease-linked mutations result in increased production of the longer form of amyloid-beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma-secretase， an enzyme that cleaves APP. Also， it is thought that the presenilins are involved in the cleavage of the Notch receptor， such that they either directly regulate gamma-secretase activity or themselves are protease enzymes. Several alternatively spliced transcript variants encoding different isoforms have been identified for this gene， the full-length nature of only some have been determined. |
| Swiss Prot | P49768 |
| Gene ID | 5663 |
| 亚细胞定位 | Cytoplasm |
| 免疫原 | Recombinant protein of human PSEN1 |
| Public Immunogen Range | 265-403aa |
| 理论分子量 | 21/42/43/46/49/52/53kDa |
| 实际分子量 | 47kDa |
| EC | |
| 纯化方法 | Affinity purification |
| 储存液 | PBS with 50% Glycerol， 0.03% Proclin300， 0.5% BSA， pH 7.3. |
| 储存条件 | Store at -20℃. Avoid freeze / thaw cycles. |
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文献和实验Polyclonal Antibody Production
, if desired this is best accomplished by Protein A Affinity Chromatography. 上一篇：make an Antibody against a Peptides 下一篇：Immunization Protocol for Monoclonal Antibody Production
Polyclonal Antibody Production
Polyclonal Antibody Production Very useful for rapid and simple generation of antibodies for western blots, ELISA assays, and immunoprecipitation. Rabbit Immunization Initial Preparation Your antigen
a simple ELISA method to detect human anti-antibody response.
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