Rabbit anti-UCP3 Polyclonal An

别名：兔抗UCP3多克隆抗体A synthesized peptide derived from Human UCP3(Accession P55916), corresponding to amino acid residues S248-F272. WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000Store at -20 °C for one year. Avoid repeated freeze/thaw cyclesWB,IHC,ELISA见优宁维官网RabbitHuman;Mouse;Rat

克隆性：见优宁维官网

产品描述：

The uncoupling protein UCP1 (formerly designated UCP) is an integral membrane protein unique to brown adipose tissue mitochondria. UCP1 forms a dimer that acts as a proton channel, which can uncouple oxidative phosphorylation by dissipating the electrochemical potential across the inner mitochondrial membrane. This process induces heat production in brown adipose tissue and is involved in regulation of body temperature and glucose metabolism. UCP2 is a structurally related protein that also uncouples mitochondrial respiration. It is more widely expressed in human and mouse tissues, including white adipose tissue and muscle, than is UCP1. UCP2 is thought to play a role in body weight regulation. An additional UCP family member, UCP3, is highly muscle specific and is possibly involved in the uncoupling of oxidative phosphorylation in skeletal muscle.

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