Rabbit anti-F10 Polyclonal Ant

别名：兔抗F10多克隆抗体A synthesized peptide derived from Human F10(Accession P00742), corresponding to amino acid residues T453-I482.WB: 1:500-1:2000, IHC: 1:50-1:200, ELISA: 1:20000-1:40000Store at -20 °C for one year. Avoid repeated freeze/thaw cyclesElisa,IHC,WB,other见优宁维官网RabbitHuman;Mouse;Rat

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产品描述：

This gene encodes the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds; the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene result in factor X deficiency, a hemorrhagic condition of variable severity. [provided by RefSeq, Jul 2008]

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