Rabbit anti-IL12B Polyclonal A

别名：兔抗IL12B多克隆抗体A synthesized peptide derived from Human IL12B(Accession P29460), corresponding to amino acid residues F269-K293.WB: 1:500-1:2000, IHC: 1:50-1:200, ELISA: 1:20000-1:40000Store at -20 °C for one year. Avoid repeated freeze/thaw cyclesElisa,IHC,WB,other见优宁维官网RabbitHuman;Mouse

克隆性：见优宁维官网

产品描述：

Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC.;Associates with IL23A to form the IL-23 interleukin, an heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to an heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.

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