- ￥480 - 1600
- Solarbio|ActivAb
- 北京
- K112284P
- 2025年08月20日
- Rabbit
- Human;Mouse;Rat
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- 详细信息
- 技术资料
- 免疫原：
Recombinant protein of human MAEA
- 亚型：
IgG
- 保存条件：
Store at -20℃. Avoid freeze / thaw cycles.
- 克隆性：
Polyclonal Antibody
- 标记物：
Biotin，Cy3，Cy3.5，Cy5，Cy5.5，Cy7，FITC，HRP，RBITC，Solar Fluor 350，Solar Fluor 405，Solar Fluor 488，Solar Fluor 532，Solar Fluor 555，Solar Fluor 568，Solar Fluor 594，Solar Fluor 633，Solar Fluor 640，Solar Fluor 647，Solar Fluor 660，Solar Fluor 680，Solar Fluor 750
- 适应物种：
Human;Mouse;Rat
- 抗原来源：
Recombinant protein of human MAEA
- 目录编号：
10296
- 级别：
实验级别
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 宿主：
Rabbit
- 浓度：
WB 1:2000-5000. IHC 1:50-200.
- 靶点：
MAEA
- 抗体英文名：
Anti-MAEA Polyclonal Antibody
- 抗体名：
巨噬细胞成红细胞附着因子抗体
- 规格：
20ul/100ul/50ul
| 规格： | 20ul | 产品价格： | ￥480.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1600.0 |
| 规格： | 50ul | 产品价格： | ￥960.0 |
| 基本信息 | |
| 英文名称 | Anti-MAEA Polyclonal Antibody |
| 中文名称 | 巨噬细胞成红细胞附着因子抗体 |
| 宿主 | Rabbit |
| 克隆类型 | Polyclonal Antibody |
| 亚型 | IgG |
| 交叉反应 | Human;Mouse;Rat |
| 预测交叉反应 | Bovine;Chicken;Orangutan |
| 稀释比例 | WB 1:2000-5000. IHC 1:50-200. |
| 密度 | |
| 靶标 | MAEA |
| 别名 | 1110030D19Rik; Cell proliferation inducing gene 5 protein; Cell proliferation-inducing gene 5 protein; EMLP; EMP; Erythroblast macrophage protein; GID complex subunit 9 FYV10 homolog; GID9; HLC 10; HLC-10; HLC10; Human lung cancer oncogene 10 protein; Lung cancer related protein 10; Macrophage erythroblast attacher; MAEA; MAEA_HUMAN; MGC93683; PIG5; Proliferation inducing gene 5 |
| 背景说明 | Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. MAEA and RMND5A are both required for catalytic activity of the CTLH E3 ubiquitin-protein ligase complex (PubMed:29911972).MAEA is required for normal cell proliferation (PubMed:29911972).The CTLH E3 ubiquitin-protein ligase complex is not required for the degradation of enzymes involved in gluconeogenesis, such as FBP1 (PubMed:29911972).Plays a role in erythroblast enucleation during erythrocyte maturation and in the development of mature macrophages (By similarity).Mediates the attachment of erythroid cell to mature macrophages; this MAEA-mediated contact inhibits erythroid cell apoptosis (PubMed:9763581).Participates in erythroblastic island formation, which is the functional unit of definitive erythropoiesis. Associates with F-actin to regulate actin distribution in erythroblasts and macrophages (By similarity).May contribute to nuclear architecture and cells division events (Probable). |
| Swiss Prot | Q7L5Y9 |
| Gene ID | 10296 |
| 亚细胞定位 | Cytoplasm Nucleus |
| 免疫原 | Recombinant protein of human MAEA |
| Public Immunogen Range | 1-350aa |
| 理论分子量 | 27/36/40/41/45kDa |
| 实际分子量 | 47kDa |
| EC | |
| 纯化方法 | Affinity purification |
| 储存液 | PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3. |
| 储存条件 | Store at -20℃. Avoid freeze / thaw cycles. |
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K112284P Anti-MAEA Polyclonal Antibody
￥480 - 1600
