- ￥480 - 1600
- Solarbio|ActivAb
- 北京
- K112242P
- 2025年08月13日
- Rabbit
- Human;Mouse
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Recombinant protein of human DNAJB12
- 亚型：
IgG
- 保存条件：
Store at -20℃. Avoid freeze / thaw cycles.
- 克隆性：
Polyclonal Antibody
- 标记物：
Biotin，Cy3，Cy3.5，Cy5，Cy5.5，Cy7，FITC，HRP，RBITC，Solar Fluor 350，Solar Fluor 405，Solar Fluor 488，Solar Fluor 532，Solar Fluor 555，Solar Fluor 568，Solar Fluor 594，Solar Fluor 633，Solar Fluor 640，Solar Fluor 647，Solar Fluor 660，Solar Fluor 680，Solar Fluor 750
- 适应物种：
Human;Mouse
- 抗原来源：
Recombinant protein of human DNAJB12
- 目录编号：
54788
- 级别：
实验级别
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 宿主：
Rabbit
- 浓度：
WB 1:1000-3000. IHC 1:50-200.
- 靶点：
DNAJB12
- 抗体英文名：
Anti-DNAJB12 Polyclonal Antibody
- 抗体名：
DnaJ(Hsp40)同系物B亚家族成员12抗体
- 规格：
20ul/100ul/50ul
| 规格： | 20ul | 产品价格： | ￥480.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1600.0 |
| 规格： | 50ul | 产品价格： | ￥960.0 |
| 基本信息 | |
| 英文名称 | Anti-DNAJB12 Polyclonal Antibody |
| 中文名称 | DnaJ(Hsp40)同系物B亚家族成员12抗体 |
| 宿主 | Rabbit |
| 克隆类型 | Polyclonal Antibody |
| 亚型 | IgG |
| 交叉反应 | Human;Mouse |
| 预测交叉反应 | Bovine |
| 稀释比例 | WB 1:1000-3000. IHC 1:50-200. |
| 密度 | |
| 靶标 | DNAJB12 |
| 别名 | DJ10; DJB12_HUMAN; DKFZp586B2023; DnaJ (Hsp40) homolog, subfamily B, member 12; DnaJ homolog subfamily B member 12; Dnajb12 |
| 背景说明 | Acts as a co-chaperone with HSPA8/Hsc70; required to promote protein folding and trafficking, prevent aggregation of client proteins, and promote unfolded proteins to endoplasmic reticulum-associated degradation (ERAD) pathway (PubMed:21150129, PubMed:21148293).Acts by determining HSPA8/Hsc70's ATPase and polypeptide-binding activities (PubMed:21148293).Can also act independently of HSPA8/Hsc70: together with DNAJB14, acts as a chaperone that promotes maturation of potassium channels KCND2 and KCNH2 by stabilizing nascent channel subunits and assembling them into tetramers (PubMed:27916661).While stabilization of nascent channel proteins is dependent on HSPA8/Hsc70, the process of oligomerization of channel subunits is independent of HSPA8/Hsc70 (PubMed:27916661).When overexpressed, forms membranous structures together with DNAJB14 and HSPA8/Hsc70 within the nucleus; the role of these structures, named DJANGOs, is still unclear (PubMed:24732912).(Microbial infection) In case of infection by polyomavirus, involved in the virus endoplasmic reticulum membrane penetration and infection (PubMed:21673190, PubMed:24675744). |
| Swiss Prot | Q9NXW2 |
| Gene ID | 54788 |
| 亚细胞定位 | Cytoplasm |
| 免疫原 | Recombinant protein of human DNAJB12 |
| Public Immunogen Range | 1-171aa |
| 理论分子量 | 42kDa |
| 实际分子量 | 42kDa |
| EC | |
| 纯化方法 | Affinity purification |
| 储存液 | PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3. |
| 储存条件 | Store at -20℃. Avoid freeze / thaw cycles. |
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文献和实验Polyclonal Antibody Production
, if desired this is best accomplished by Protein A Affinity Chromatography. 上一篇：make an Antibody against a Peptides 下一篇：Immunization Protocol for Monoclonal Antibody Production
Polyclonal Antibody Production
Polyclonal Antibody Production Very useful for rapid and simple generation of antibodies for western blots, ELISA assays, and immunoprecipitation. Rabbit Immunization Initial Preparation Your antigen
a simple ELISA method to detect human anti-antibody response.
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