- ￥960
- Solarbio
- K112284P-50ul
- 北京
- 2025年12月22日
- WB IHC
- Rabbit
- Human;Mouse;Rat
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- 详细信息
- 文献和实验
- 技术资料
- 靶点：
MAEA
- 应用范围：
WB IHC
- 宿主：
Rabbit
- 适应物种：
Human;Mouse;Rat
- 保质期：
一年
- 供应商：
北京索莱宝科技有限公司
- 克隆性：
Polyclonal Antibody
- 保存条件：
Store at -20℃. Avoid freeze / thaw cycles.
- 亚型：
IgG
- 免疫原：
Recombinant protein of human MAEA
- 规格：
50ul
| 中文名称 | 巨噬细胞成红细胞附着因子抗体 |
| 靶标 | MAEA |
| 别名 | 1110030D19Rik; Cell proliferation inducing gene 5 protein; Cell proliferation-inducing gene 5 protein; EMLP; EMP; Erythroblast macrophage protein; GID complex subunit 9 FYV10 homolog; GID9; HLC 10; HLC-10; HLC10; Human lung cancer oncogene 10 protein; Lung cancer related protein 10; Macrophage erythroblast attacher; MAEA; MAEA_HUMAN; MGC93683; PIG5; Proliferation inducing gene 5 |
| 背景资料 | Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. MAEA and RMND5A are both required for catalytic activity of the CTLH E3 ubiquitin-protein ligase complex (PubMed:29911972).MAEA is required for normal cell proliferation (PubMed:29911972).The CTLH E3 ubiquitin-protein ligase complex is not required for the degradation of enzymes involved in gluconeogenesis, such as FBP1 (PubMed:29911972).Plays a role in erythroblast enucleation during erythrocyte maturation and in the development of mature macrophages (By similarity).Mediates the attachment of erythroid cell to mature macrophages; this MAEA-mediated contact inhibits erythroid cell apoptosis (PubMed:9763581).Participates in erythroblastic island formation, which is the functional unit of definitive erythropoiesis. Associates with F-actin to regulate actin distribution in erythroblasts and macrophages (By similarity).May contribute to nuclear architecture and cells division events (Probable). |
| Swiss Prot | Q7L5Y9 |
| Gene ID | 10296 |
| 亚细胞定位 | Cytoplasm Nucleus |
| 宿主 | Rabbit |
| 克隆类型 | Polyclonal Antibody |
| 亚型 | IgG |
| 预测交叉反应 | Bovine;Chicken;Orangutan |
| 蛋白分子量 | 27/36/40/41/45kDa |
| 实际分子量 | 47kDa |
| 稀释比例 | WB 1:2000-5000. IHC 1:50-200. |
| 免疫原 | Recombinant protein of human MAEA |
| Public Immunogen Range | 1-350aa |
| 纯化方法 | Affinity purification |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 保存 | Store at -20℃. Avoid freeze / thaw cycles. |
| 交叉反应 | Human;Mouse;Rat |
| 应用 | WB IHC |
| 规格 | 50ul 100ul |
| 单位 | 支 |
备注：
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these methods.
实验图
"Western blot analysis with MAEA antibody diluted at 1:2000;Lane: HepG2
Immunohistochemistry of paraffin-embedded human breast cancer with MAEA antibody diluted at 1:100.
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文献和实验Polyclonal Antibody Production
, if desired this is best accomplished by Protein A Affinity Chromatography. 上一篇：make an Antibody against a Peptides 下一篇：Immunization Protocol for Monoclonal Antibody Production
Polyclonal Antibody Production
Polyclonal Antibody Production Very useful for rapid and simple generation of antibodies for western blots, ELISA assays, and immunoprecipitation. Rabbit Immunization Initial Preparation Your antigen
a simple ELISA method to detect human anti-antibody response.
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