K110951P Anti-TNIP1 Polyclonal Antibody

K110951P Anti-TNIP1 Polyclonal

Antibody
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  • ¥480 - 1600
  • Solarbio|ActivAb
  • 北京
  • K110951P
  • 2025年08月13日
  • WB;IHC
  • Rabbit
  • Human
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    • 详细信息
    • 技术资料
    • 免疫原

      Recombinant protein of human TNIP1

    • 亚型

      IgG

    • 保存条件

      Store at -20℃. Avoid freeze/thaw cycles.

    • 克隆性

      Polyclonal Antibody

    • 标记物

      Biotin,Cy3,Cy3.5,Cy5,Cy5.5,Cy7,FITC,HRP,RBITC,Solar Fluor 350,Solar Fluor 405,Solar Fluor 488,Solar Fluor 532,Solar Fluor 555,Solar Fluor 568,Solar Fluor 594,Solar Fluor 633,Solar Fluor 640,Solar Fluor 647,Solar Fluor 660,Solar Fluor 680,Solar Fluor 750

    • 适应物种

      Human

    • 抗原来源

      Recombinant protein of human TNIP1

    • 目录编号

      10318

    • 级别

      实验级别

    • 库存

      现询

    • 供应商

      北京索莱宝科技有限公司

    • 宿主

      Rabbit

    • 应用范围

      WB;IHC

    • 浓度

      WB 1:1000-3000. IHC 1:100-300.

    • 靶点

      TNIP1

    • 抗体英文名

      Anti-TNIP1 Polyclonal Antibody

    • 抗体名

      TNFAIP3相互作用蛋白1抗体

    • 规格

      20ul/100ul/50ul

    规格:20ul产品价格:¥480.0
    规格:100ul产品价格:¥1600.0
    规格:50ul产品价格:¥960.0
    基本信息
    英文名称Anti-TNIP1 Polyclonal Antibody
    中文名称TNFAIP3相互作用蛋白1抗体
    宿主Rabbit
    克隆类型Polyclonal Antibody
    亚型IgG
    交叉反应Human;Mouse
    应用WB;IHC
    稀释比例WB 1:1000-3000. IHC 1:100-300.
    密度
    靶标TNIP1
    别名ABIN-1;Naf1;Nip40-1;VAN;hVAN;KIAA0113;NAF1;
    背景说明Inhibits NF-kappa-B activation and TNF-induced NF-kappa-B-dependent gene expression by regulating A20/TNFAIP3-mediated deubiquitination of IKBKG; proposed to link A20/TNFAIP3 to ubiquitinated IKBKG. Involved in regulation of EGF-induced ERK1/ERK2 signaling pathway; blocks MAPK3/MAPK1 nuclear translocation and MAPK1-dependent transcription. Increases cell surface CD4(T4) antigen expression. Involved in the anti-inflammatory response of macrophages and positively regulates TLR-induced activation of CEBPB. Involved in the prevention of autoimmunity; this function implicates binding to polyubiquitin. Involved in leukocyte integrin activation during inflammation; this function is mediated by association with SELPLG and dependent on phosphorylation by SRC-family kinases. Interacts with HIV-1 matrix protein and is packaged into virions and overexpression can inhibit viral replication. May regulate matrix nuclear localization, both nuclear import of PIC (Preintegration complex) and export of GAG polyprotein and viral genomic RNA during virion production. In case of infection, promotes association of IKBKG with Shigella flexneri E3 ubiquitin-protein ligase ipah9.8 p which in turn promotes polyubiquitination of IKBKG leading to its proteasome-dependent degradation and thus is perturbing NF-kappa-B activation during bacterial infection.
    Swiss ProtQ15025
    Gene ID10318
    亚细胞定位Cytoplasm Nucleus
    免疫原Recombinant protein of human TNIP1
    Public Immunogen Range1-350aa
    理论分子量62/63/64/65/66/72kDa
    EC
    纯化方法Octanoic acid-ammonium sulfate precipitation
    储存液PBS with 50% Glycerol,0.03% Proclin300,0.5% BSA,pH 7.3.
    储存条件Store at -20℃. Avoid freeze/thaw cycles.

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