K112810P Anti-LATS1/LATS2 Polyclonal Antibody

K112810P Anti-LATS1/LATS2 Poly

clonal Antibody
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  • ¥480 - 1600
  • Solarbio|ActivAb
  • 北京
  • K112810P
  • 2025年08月13日
  • IHC
  • Rabbit
  • Mouse;Human;Rat
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    • 详细信息
    • 技术资料
    • 免疫原

      A synthetic peptide of human LATS1/LATS2

    • 亚型

      IgG

    • 保存条件

      Store at -20℃. Avoid freeze / thaw cycles.

    • 克隆性

      Polyclonal Antibody

    • 标记物

      Biotin,Cy3,Cy3.5,Cy5,Cy5.5,Cy7,FITC,HRP,RBITC,Solar Fluor 350,Solar Fluor 405,Solar Fluor 488,Solar Fluor 532,Solar Fluor 555,Solar Fluor 568,Solar Fluor 594,Solar Fluor 633,Solar Fluor 640,Solar Fluor 647,Solar Fluor 660,Solar Fluor 680,Solar Fluor 750

    • 适应物种

      Mouse;Human;Rat

    • 抗原来源

      A synthetic peptide of human LATS1/LATS2

    • 目录编号

      9113/26524

    • 级别

      实验级别

    • 库存

      现询

    • 供应商

      北京索莱宝科技有限公司

    • 宿主

      Rabbit

    • 应用范围

      IHC

    • 浓度

      IHC 1:50-200.

    • 靶点

      LATS1/LATS2

    • 抗体英文名

      Anti-LATS1/LATS2 Polyclonal Antibody

    • 抗体名

      h-warts; Large tumor suppressor homolog 1; LATS large tumor suppressor homolog 1; LATS1; LATS1_HUMAN; Serine threonine protein kinase LATS1; Serine/threonine-protein kinase LATS1; WARTS; WARTS protein kinase; wts;

    • 规格

      20ul/100ul/50ul

    规格:20ul产品价格:¥480.0
    规格:100ul产品价格:¥1600.0
    规格:50ul产品价格:¥960.0
    基本信息
    英文名称Anti-LATS1/LATS2 Polyclonal Antibody
    宿主Rabbit
    克隆类型Polyclonal Antibody
    亚型IgG
    交叉反应Mouse;Human;Rat
    预测交叉反应Cow(91.7%);Rabbit(91.7%);Chicken(91.7%);Pig(91.7%);Sheep(91.7%);Fruit fly(100%);Zebrafish(90.9%);Xenopus laevis(91.7%);Yeast(93.3%);Saccharomyces cerevisiae(93.3%);Fungi(84.6%);Candida albicans(93.3%);Rice(84.6%);Arabidopsis thaliana(90.9%);Worm(85.7%);Caenorhabditis elegans(91.7%)
    应用IHC
    稀释比例IHC 1:50-200.
    密度
    靶标LATS1/LATS2
    别名h-warts; Large tumor suppressor homolog 1; LATS large tumor suppressor homolog 1; LATS1; LATS1_HUMAN; Serine threonine protein kinase LATS1; Serine/threonine-protein kinase LATS1; WARTS; WARTS protein kinase; wts;
    背景说明The protein encoded by this gene is a putative serine/threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis. The protein is phosphorylated in a cell-cycle dependent manner, with late prophase phosphorylation remaining through metaphase. The N-terminal region of the protein binds CDC2 to form a complex showing reduced H1 histone kinase activity, indicating a role as a negative regulator of CDC2/cyclin A. In addition, the C-terminal kinase domain binds to its own N-terminal region, suggesting potential negative regulation through interference with complex formation via intramolecular binding. Biochemical and genetic data suggest a role as a tumor suppressor. This is supported by studies in knockout mice showing development of soft-tissue sarcomas, ovarian stromal cell tumors and a high sensitivity to carcinogenic treatments.
    Swiss ProtO95835/Q9NRM7
    Gene ID9113/26524
    亚细胞定位Cytoplasm
    免疫原A synthetic peptide of human LATS1/LATS2
    Public Immunogen Range800-850/1130aa
    理论分子量76/127KDa
    EC
    纯化方法Octanoic acid-ammonium sulfate precipitation
    储存液PBS with 50% Glycerol,0.03% Proclin300,0.5% BSA,pH 7.3.
    储存条件Store at -20℃. Avoid freeze / thaw cycles.

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