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Anti-GBA / GCase Recombinant R

abbit Monoclonal Ab
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  • ¥860
  • Elucigen Biosciences
  • ERB0458
  • 2025年08月13日
  • ICC, IHC, WB
  • Rabbit
  • Human
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  • 企业认证

    • 详细信息
    • 文献和实验
    • 技术资料
    • 免疫原

      Synthetic peptide corresponding to the C-terminal region of human GBA.

    • 亚型

      IgG

    • 形态

      Liquid

    • 保存条件

      -20°C

    • 克隆性

      Monoclonal

    • 标记物

      Unconjugated

    • 适应物种

      Human

    • 保质期

      12 months from the shipping date of the product.

    • 抗原来源

      Human

    • 目录编号

      ERB0458

    • 级别

      Primary Antibodies

    • 库存

      Available

    • 供应商

      Elucigen Biosciences

    • 宿主

      Rabbit

    • 应用范围

      ICC, IHC, WB

    • 浓度

      0.5 mg/mL

    • 靶点

      P04062

    • 抗体英文名

      Anti-GBA / GCase Recombinant Rabbit Monoclonal Ab

    • 抗体名

      Anti-GBA / GCase Recombinant Rabbit Monoclonal Ab

    • 规格

      25μg/100μg/500μg

    规格:25μg产品价格:¥860.0
    规格:100μg产品价格:询价
    规格:500μg产品价格:询价
    Lysosomal acid glucosylceramidase (GBA), also known as glucocerebrosidase, is an enzyme responsible for the breakdown of glucocerebroside, a type of lipid, within the lysosomes. It catalyzes the hydrolysis of glucocerebroside to produce glucose and ceramide, which are essential components for maintaining cellular lipid balance. GBA is crucial for proper lysosomal function, and its deficiency leads to the accumulation of glucocerebroside in various tissues, which is the hallmark of Gaucher disease, a genetic disorder. Gaucher disease manifests in a range of symptoms, including enlarged spleen and liver, bone issues, and neurological complications. Research into GBA focuses on understanding its role in lipid metabolism and developing therapies for Gaucher disease and related conditions.

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    图标文献和实验
    该产品被引用文献
    Mazzulli, J.R. et al. (2011) Cell 146, 37-52.
    相关实验
    • Indirect Immunofluorescence

      Reagents:  NGS-Normal Goat Serum  PBST-0.5% Tween-20/CMF-PBS  CMF-PBS  1°Ab-mouse MF20 (anti-myosin monoclonal)  1°Ab-rabbit myoD (anti-myoD polyclonal)  2°Ab-goat anti-mouse IgG-FITC  2°Ab-goat anti-rabbit IgG-FITC

    • ELISA PROTOCOL 【Yale University 】

      -nitrophenyl phosphate (5 mg/tablet). SigmaCat.# N93895) AP-conjugated secondary Ab: AP-Rabbit anti-mouse IgG(Zymed). Reconstitute in ddH2O as prescribed by manufacturer andaliquot and store at -70 °C.6) 100 mM EDTA pH

    • (共享)蛋白分析方法之免疫沉淀

      Protein A-Sepharose and analyzed by SDS-PAGE and fluorography. Lanes represent proteins immunoprecipitated with rabbit antiserum to UTMP (Ab), normal rabbit serum in place of antiserum (NRS) and the total array of radiolabeled proteins present

    图标技术资料

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    文献支持
    Anti-GBA / GCase Recombinant Rabbit Monoclonal Ab
    ¥860