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- 保存条件:
详询
- 保质期:
详询
- 库存:
50
- 供应商:
广州市左克生物
- 规格:
100T/25T
| 规格: | 100T | 产品价格: | ¥6559.0 |
|---|---|---|---|
| 规格: | 25T | 产品价格: | ¥2079.0 |
产品简介:
品牌:MultiSciences/联科生物
货号:70-KTR101-100///70-KTR101-25
产品简介
调节性T细胞(Tregs),曾被称为抑制性T细胞,是T细胞的亚群,可调节免疫系统、维持对自身抗原的耐受、抑制自身免疫疾病。Tregs具有免疫抑制性,可抑制或下调效应T细胞的诱导和增殖。调节性T细胞有多种类型,其中研究最深的的一类表达CD4、CD25和FOXP3(CD4+CD25+调节性T细胞)。免疫系统必须能区分自我和非我。当自我/非我无法识别时,免疫系统会破坏细胞和组织,引起自身免疫疾病。调节性T细胞积极地抑制免疫系统活化、阻止病理性的自身反应如自身免疫疾病。调节性T细胞遗传缺失造成的重度自身免疫综合征(IPEX综合征)表明调节性T细胞在免疫系统中发挥了重要作用。
产品特点
- 即用型,无需购买其他产品;
- 灵敏度高,特异性强,结果稳定;
- 价格便宜,现货供应。
结果示例

Flow cytometric analysis of Human Regulatory T Cell Staining Kit. The staining pattern of FSC/CD4 (Left),CD25/Rat IgG2a Isotype Control, PE (Middle) and CD25/FoxP3 (Right) on human anticoagulant blood. Adherent cells have been excluded. Flow cytometry was performed on a Thermo Fisher Attune NxT.
使用Human Regulatory T Cell Staining Kit进行流式检测。人抗凝血染色FSC/CD4 (左), CD25/大鼠IgG2a同型对照, PE (中)和CD25/FoxP3(右)。粘连细胞已被排除。实验在Thermo Fisher公司的Attune NxT流式细胞仪上进行。
试剂盒组分
| 组分 | 编号 | 25Test | 100Test |
| 抗人CD4, FITC (克隆号:RPA-T4) | AH00401 | 150 μl | 550 μl |
| 抗人CD25, APC (克隆号:BC96) | AH02505 | 150 μl | 550 μl |
| 抗人FoxP3, PE (克隆号:PCH101) | AH0F04 | 150 μl | 550 μl |
| 大鼠IgG2a同型对照, PE | CMG2a04 | 25 μl | 100 μl |
| 正常大鼠血清 | NRS | 60 μl | 250 μl |
| 固定破膜剂浓缩液(4×) | ICC01 | 8 ml | 30 ml |
| 固定破膜剂稀释液 | ICD01 | 25 ml | 100 ml |
| 破膜缓冲液(10×) | ICB01 | 25 ml | 100 ml |
| 红细胞裂解液(不含固定剂) (10×) | LYS | 8 ml | 30 ml |
| 流式染色缓冲液(10×) | S1002 | 15 ml | 60 ml |
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文献和实验Depletion of Human Regulatory T Cells
Regulatory T cells (Treg) have become increasingly relevant in the study of human disease including cancer. Treg cells have been shown to inhibit anti-tumor immune responses, and elevated Treg levels have been associated with certain types
Flow Cytometric Detection of Human Regulatory T Cells
abnormalities contribute to the pathogenesis of sporadic autoimmune, allergic and immunoinflammatory diseases in man remains controversial. Robust methods for identifying and isolating human Tregs in patients and healthy controls are essential
Methods for In Vitro Generation of Human Type 1 Regulatory T Cells
Type 1 regulatory T (Tr1) cells are adaptive regulatory T cells that are induced in the periphery upon chronic exposure to antigen (Ag) in a tolerogenic environment containing interleukin (IL)-10. Tr1 cells are Ag-specific; they produce high
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