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- 详细信息
- 技术资料
- 库存:
现询
- 供应商:
北京索莱宝科技有限公司
- 规格:
1mg/500ug/50ug/10ug
| 规格: | 1mg | 产品价格: | ¥21120.0 |
|---|---|---|---|
| 规格: | 500ug | 产品价格: | ¥14784.0 |
| 规格: | 50ug | 产品价格: | ¥3276.0 |
| 规格: | 10ug | 产品价格: | ¥1092.0 |
| 基本信息 | |
| 基因名 | |
| 别名 | Endoglin;END;CD105;ENG |
| 外观(性状) | Supplied as a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
| 运输条件 | 干冰运输 |
| 背景说明 | Endoglin is a single-pass type I membrane protein which restricted to endothelial cells in all tissues except bone marrow.Endoglin as major glycoprotein of vascular endothelium,it has been found on endothelial cells,activated macrophages,fibroblasts,and smooth muscle cells.Furthermore,Homodimer forms a heteromeric complex with the signaling receptors for transforming growth factor-beta: TGFBR1 and/or TGFBR2.It may have an important role in the binding of endothelial cells to integrins and/or other RGD receptors.Defects in ENG are the cause of hereditary hemorrhagic telangiectasia type 1 (HHT1),which is an autosomal dominant multisystemic vascular dysplasia,characterized by recurrent epistaxis,muco-cutaneous telangiectases,gastro-intestinal hemorrhage,and pulmonary (PAVM),cerebral (CAVM) and hepatic arteriovenous malformations. |
| 来源 | E.coli |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
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P01253 Recombinant Human CD105/Endoglin 细胞因子/蛋白
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