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- P01233
- 北京
- 2025年07月25日
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￥1092
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- 详细信息
- 文献和实验
- 技术资料
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 规格：
1mg/500ug/50ug/10ug
| 规格： | 1mg | 产品价格： | ￥21120.0 |
|---|---|---|---|
| 规格： | 500ug | 产品价格： | ￥14784.0 |
| 规格： | 50ug | 产品价格： | ￥3276.0 |
| 规格： | 10ug | 产品价格： | ￥1092.0 |
| 基本信息 | |
| 基因名 | |
| 别名 | Protein Phosphatase 1 Regulatory Subunit 14A;17 kDa PKC-Potentiated Inhibitory Protein of PP1;Protein Kinase C-Potentiated Inhibitor Protein of 17 kDa;CPI-17;PPP1R14A;CPI17;PPP1INL |
| 外观(性状) | Supplied as a 0.2 μm filtered solution of 20mM TrisHCl, 0.2mM EDTA, 1mM DTT, 10% Glycerol, pH 8.0. |
| 纯度 | ≥85% as determined by reducing SDS-PAGE. |
| 储存条件 | Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
| 运输条件 | 干冰运输 |
| 背景说明 | Protein Phosphatase 1 Regulatory Subunit 14A (PPP1R14A) belongs to the PP1 inhibitor family.PPP1R14A is mapped to chromosome 19q13.13-q13.2.PPP1R14A binds directly to protein kinase C and casein kinase I.Meantime，PPP1R14A is a phosphorylation-dependent inhibitor of smooth muscle myosin phosphatase.PPP1R14A is the inhibitor of PPP1CA.When phosphorylated，PPP1R14A has over 1000-fold higher inhibitory activity，creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction.In addition，inhibition of PPP1R14A also enhances contraction of smooth muscle in the absence of increment of intracellular Ca2+ concentration. |
| 来源 | E.coli |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
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文献和实验DETECTION OF ß-GALACTOSIDASE AND ALKALINE PHOSPHATASE ACTIVITIES IN TISSUE
in the developing striatum. Neuron 9 :15. Henthorn, P., P. Zervos, M. Raducha, H. Harris, and T. Kadesch. 1988. Expression of a human placental alkaline phosphatase gene in transfected cells: Use as a reporter for studies of gene expression. Proc. Natl
Microarray Approaches for Analysis of Cell Cycle Regulatory Genes
genes is also known to play an important role in disease states such as genomic instability and cancer. For instance, p53, a cell cycle regulatory transcription factor, is also one of the most commonly mutated tumor-suppressor genes in human cancer
Strategies to Optimize Protein Expression in E. coli
Peng, L., Xu, Z.N., Fang, X.M., Wang, F., Yang, S., and Cen, P.L. 2004. Preferential codons enhancing the expression level of human beta‐defensin‐2 in recombinant Escherichia coli. Protein Pept. Lett. 11:339
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