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P00869 Recombinant Mouse BTNL2

/Butyrophilin-like Protein 2 细胞因子/蛋白
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  • ¥936 - 15360
  • Solarbio已认证
  • P00869
  • 北京
  • 2025年07月25日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 库存

      现询

    • 供应商

      北京索莱宝科技有限公司

    • 规格

      1mg/500ug/50ug/10ug

    规格:1mg产品价格:¥15360.0
    规格:500ug产品价格:¥10752.0
    规格:50ug产品价格:¥2600.0
    规格:10ug产品价格:¥936.0
    基本信息
    基因名
    别名Butyrophilin-like protein 2;Btnl2;Gm315;Ng9
    外观(性状)Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
    纯度≥95% as determined by reducing SDS-PAGE.
    储存条件Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
    运输条件The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below.
    背景说明Butyrophilin-like 2 (BTNL2) is a member of the BTN/MOG Ig-superfamily and functions as a negative regulator of immune cell activation.Mouse BTNL2 is type I transmembrane glycoprotein that contains an extracellular domain (ECD),a transmembrane region and a short cytoplasmic domain.The ECD features two V-type Ig-like domains,two C-type Ig-like domains,and four glycosylation sites.BTNL2 is expressed in epithelial cells of the small intestine,colonic dendritic cells,and in cells of the lymph node.BTNL2 expression is upregulated in T cells following activation,a characteristic BTNL2 shares with the homologous B7 family of costimulatory molecules.BTNL2 negatively regulates T cells by inhibiting proliferation and inflammatory cytokine secretion.It also increases the expression of FoxP3 in T cells to promote regulatory T cell development.Single nucleotide polymorphisms in BTNL2 are associated with a risk for sporadic prostate cancer,rheumatoid arthritis,sarcoidosis,ulcerative colitis,and other inflammatory diseases.
    来源Human Cells
    溶剂Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    内毒素Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.
    单位

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