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P01335 Recombinant Human Neurt

urin 细胞因子/蛋白
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  • ¥1092 - 21120
  • Solarbio已认证
  • P01335
  • 北京
  • 2025年07月25日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 库存

      现询

    • 供应商

      北京索莱宝科技有限公司

    • 规格

      1mg/500ug/50ug/10ug

    规格:1mg产品价格:¥21120.0
    规格:500ug产品价格:¥14784.0
    规格:50ug产品价格:¥3276.0
    规格:10ug产品价格:¥1092.0
    基本信息
    基因名
    别名Neurturin;NRTN
    外观(性状)Lyophilized from a 0.2 μm filtered solution of 10mM sodium citrate, pH4.0.
    纯度≥95% as determined by reducing SDS-PAGE.
    储存条件Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
    运输条件The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below.
    背景说明Neurturin is a member of the GDNF family of ligands,which include glial cell-derived neurotrophic factor (GDNF),Neurturin,Persephin,and Artemin.Neurturin is expressed in both neuronal and nonneuronal tissues.Similarly to other TGFβ family proteins,Neurturin is synthesized as a precursor protein that is cleaved at the dibasic cleavage site (RXXR) to release the carboxyterminal domain.The carboxy terminal domain of Neurturin contains the characteristic seven conserved cysteine residues necessary for the formation of the cysteine-knot and the single interchain disulfide bond.Biologically active human Neurturin is a disulfide-linked homodimer of the carboxy-terminal 102 amino acid residues.Unlike other members of TGF-β family,bioactivities of all GDNF family ligands are mediated through a unique multicomponent receptor complex composed of high affinity ligand binding component (GFRα-1-GFRα-4) and a common signaling component (cRET receptor tyrosine kinase).Each member of the GDNF family ligands has its preferred binding protein.Neurturin preferentially binds to GFRα-2 but can also bind GFRα-1 at higher concentrations.It may play a role in regulating the development and maintenance of the central and peripheral nervous systems and as well as non neuronal systems.
    来源E.coli
    溶剂Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    内毒素Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.
    单位

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