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- 详细信息
- 技术资料
- 库存:
现询
- 供应商:
北京索莱宝科技有限公司
- 规格:
1mg/500ug/50ug/10ug
| 规格: | 1mg | 产品价格: | ¥21120.0 |
|---|---|---|---|
| 规格: | 500ug | 产品价格: | ¥14784.0 |
| 规格: | 50ug | 产品价格: | ¥3276.0 |
| 规格: | 10ug | 产品价格: | ¥1092.0 |
| 基本信息 | |
| 基因名 | |
| 别名 | Heme Oxygenase 1;HO-1;HMOX1;HO;HO1 |
| 外观(性状) | Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, 1mM EDTA, pH 7.4. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
| 运输条件 | 干冰运输 |
| 背景说明 | Heme Oxygenase 1 (HO-1) is an enzyme in endoplasmic reticulum that belongs to the heme oxygenase family.HO-1 cleaves the heme ring at the alpha methene bridge to form Biliverdin.Biliverdin is subsequently converted to Bilirubin by Biliverdin reductase.In physiological state,the highest activity of HO-1 is found in the spleen,where senescent erythrocytes are sequestrated and destroyed.HO-1 activity is highly inducible by its substrate heme and by various non-heme substances such as heavy metals,bromobenzene,endotoxin,oxidizing agents and UVA.HO-1 is involved in the regulation of cardiovascular function and response to a variety of stressors.Defects in HO-1 are the cause of Heme Oxygenase 1 deficiency,resulting in marked erythrocyte fragmentation and intravascular hemolysis,coagulation abnormalities,endothelial damage,and iron deposition in renal and hepatic tissues. |
| 来源 | E.coli |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
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