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- 详细信息
- 文献和实验
- 技术资料
- 库存:
现询
- 供应商:
北京索莱宝科技有限公司
- 规格:
1mg/500ug/50ug/10ug
| 规格: | 1mg | 产品价格: | ¥21120.0 |
|---|---|---|---|
| 规格: | 500ug | 产品价格: | ¥14784.0 |
| 规格: | 50ug | 产品价格: | ¥3276.0 |
| 规格: | 10ug | 产品价格: | ¥1092.0 |
| 基本信息 | |
| 基因名 | |
| 别名 | Ribonuclease K6;RNase K6;RNASE6;RNS6 |
| 外观(性状) | Supplied as a 0.2 μm filtered solution of 20mM TrisHCl,150mM NaCl,1mMDTT,10%Glycerol,pH7.5. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
| 运输条件 | 干冰运输 |
| 背景说明 | Ribonuclease K6 (RNASE6) is a secreted protein that belongs to the pancreatic ribonuclease family.Human RNASE6 is synthesized as a 150 amino acid precursor that contains a 23 amino acid signal sequence,and a 127 amino acid mature chain.RNASE6 is expressed in many tissues,with high expression levels in the lung,with lower expression levels in the heart,placenta,kidney,pancreas,liver,brain,and skeletal muscle.It is also detected in monocytes and neutrophils.RNASE6 may have a role in host defense. |
| 来源 | Human Cells |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
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文献和实验RNase P Ribozyme As an Antiviral Agent Against Human Cytomegalovirus
immunodeficiency syndrom (AIDS) patients (e.g., CMV-associated retinitis and pneumonia), and possibly cardiovascular diseases such as atherosclerosis. This chapter describes the utilization of RNase P ribozyme—specifically, M1GS ribozyme, as a gene-targeting agent
In Vitro Selection of External Guide Sequences for Directing Human RNase P to Cleave a Target mRNA
the targeting activity of EGSs in directing human RNase P to cleave an mRNA in vitro can lead to better efficacies of the EGSs in inducing RNase P-mediated inhibition of the expression of the target mRNA in cultured cells. This chapter
Targeting mRNAs by Engineered Sequence-Specific RNase P Ribozymes
The methods of using engineered RNase P catalytic RNA (termed as M1GS RNA) for in vitro and in vivo in trans-cleavage of target viral mRNA are described in this chapter. Detailed information is focused on (1) mapping accessible regions
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