P00138 Recombinant Human CD20

Recombinant Human CD200 is produced by our Mammalian expression system and the target gene encoding Gln31-Gly232 is expressed with a Fc tag at the C-terminus.

基本信息
基因名
别名	OX-2 Membrane Glycoprotein;CD200;MOX1;MOX2
外观(性状)	Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.
纯度	≥95% as determined by reducing SDS-PAGE.
储存条件	Powder:＜-20℃ for long store;RT，3 weeks.Liquid:4-7℃，2-7 days;＜-20℃，3 months.
运输条件	The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below.
背景说明	CD200 is a transmembrane immunoregulatory protein that belongs to the immunoglobulin superfamily.It contains one Ig like V type domain and one Ig like C2 type domain in its extracelluar domain.CD200 is widely but not ubiquitously expressed.Its receptor (CD200R) is restricted primarily to mast cells，basophils，macrophages，and dendritic cells，which suggests myeloid cell regulation as the major function of CD200.CD200 and CD200R associate via their respective N-terminal Ig-like domains.In myeloid cells，CD200R initiates inhibitory signals following receptor-ligand contact.In T cells，CD200 functions as a co-stimulatory molecule independent of the CD28 pathway.In addition，CD200 also plays an important role in prevention of graft rejection，autoimmune diseases and spontaneous abortion.
来源	Human cells
溶剂	Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素	Less than 0.1 ng/ug(1 IEU/ug)as determined by LAL test.
单位	支