P01144 Recombinant Human Lange
rin/CD207/C-type lectin domain family 4 member K/C-type lectin domain family 4, member K 细胞因子/蛋白- ￥988 - 21120
- Solarbio
- P01144
- 北京
- 2025年07月25日
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- 详细信息
- 文献和实验
- 技术资料
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 规格：
1mg/500ug/50ug/10ug
| 规格： | 1mg | 产品价格： | ￥21120.0 |
|---|---|---|---|
| 规格： | 500ug | 产品价格： | ￥14784.0 |
| 规格： | 50ug | 产品价格： | ￥2600.0 |
| 规格： | 10ug | 产品价格： | ￥988.0 |
| 基本信息 | |
| 基因名 | |
| 别名 | CD207 antigen;langerin;CD207;C-type lectin domain family 4 member K;C-type lectin domainfamily 4,member K |
| 外观(性状) | Lyophilized from a 0.2 μm filtered solution of PBS,pH 7.4. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 运输条件 | The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| 背景说明 | Langerin (CD207) is a type II transmembrane glycoprotein which is member K of the C-type lectin domain family.Langerin is used as a marker for Langerhans cells (LCs) which represent the immature dendritic cells in the epidermis.Langerin is necessary and sufficient for Birbeck granule formation.Human langerin sequence contains a 43 aa cytoplasmic domain，a 21 aa transmembrane domain and a 264 aa extracellular domain (ECD) that contains a coiled-coil domain and a single C-type lectin domain.Human langerin shares 68%，62%，71% aa identity with mouse，rat and bovine langerin ECD，respectively.Trimerization greatly increases the lectin binding affinity.Langerin internalizes endogenous proteins such as type I procollagen.Internalization by LC is thought to lead to suppression of self reactions.Langerin also mediates endocytosis of non-peptide antigens containing mannose，N-acetyl glucosamine and fucose that are expressed by mycobacteria and fungae. |
| 来源 | Human Cells |
| 溶剂 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
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