P01142 Recombinant Human CD28/TP44/T-cell-specific surface glycoprotein CD28 细胞因子/蛋白

P01142 Recombinant Human CD28/

TP44/T-cell-specific surface glycoprotein CD28 细胞因子/蛋白
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  • ¥988 - 21120
  • Solarbio已认证
  • P01142
  • 北京
  • 2025年07月25日
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    • 详细信息
    • 技术资料
    • 库存

      现询

    • 供应商

      北京索莱宝科技有限公司

    • 规格

      1mg/500ug/50ug/10ug

    规格:1mg产品价格:¥21120.0
    规格:500ug产品价格:¥14784.0
    规格:50ug产品价格:¥2600.0
    规格:10ug产品价格:¥988.0
    基本信息
    基因名
    别名CD28;CD28 antigen;CD28 molecule;T-cell-specific surface glycoprotein CD28;Tp44;TP44
    外观(性状)Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    纯度≥95% as determined by reducing SDS-PAGE.
    储存条件Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
    运输条件The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below.
    背景说明T-cell-specific surface glycoprotein CD28(CD28) is a single-pass typeI membrane protein which contains one Ig-likeV-type (immunoglobulin-like)domain.It belongs to the immunoglobulin(Ig) superfamily.CD28 is one of the molecules expressed on T cells that provide co-stimulatory signals,which are required for T cell activation.CD28 co-stimulation is necessary for CD4 positive T-cell proliferation and survival,interleukin-2 production,and T-helper type-2 development.Human post-thymic regulatory T cells require CD28 co-stimulation to expand and maintain potent suppressive function in vivo.Apoptosis plays a key role in the age-related decline of CD28 expression and in immunosenescence.CD28 is the receptor for CD80(B7.1) and CD86(B7.2).When activated by Toll-like receptor ligands,the CD80 expression is upregulated in antigen presenting cells(APCs).The CD86 expression on antigen presenting cells is constitutive.CD28 is the only B7 receptor constitutively expressed on naive T cells.
    来源Human Cells
    溶剂Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    内毒素Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.
    单位

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    ¥988 - 21120