- ￥988 - 21120
- Solarbio
- P01109
- 北京
- 2025年07月25日
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- 详细信息
- 文献和实验
- 技术资料
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 规格：
1mg/500ug/50ug/10ug
| 规格： | 1mg | 产品价格： | ￥21120.0 |
|---|---|---|---|
| 规格： | 500ug | 产品价格： | ￥14784.0 |
| 规格： | 50ug | 产品价格： | ￥2600.0 |
| 规格： | 10ug | 产品价格： | ￥988.0 |
| 基本信息 | |
| 基因名 | |
| 别名 | Receptor activator of NF-KB;tumor necrosis factor receptor superfamily member 11A;TRANCE receptor;Osteoclast differentiation factor receptor;NFKB activator;TRANCER;CD265;TNFRSF11A;TRANCE R;CD265 antigen;ODFR |
| 外观(性状) | Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 运输条件 | The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| 背景说明 | Receptor activator of NF-κB(RANK，TNFRSF11A) belongs to one member oftumor necrosis factor receptor family.It is a receptor for TNFSF11/RANKL/TRANCE/OPGL.This gene encodes a type 1 membrane protein with a 30 amino acids (aa) signal peptide，184 aa extracellular region，a 20 aa transmembrane domain and a 391 aa cytoplasmic region.Human and murine RANK share 81% aa identity in their extracellular domains.RANK is ubiquitous highly expressed in trabecular bone，thymus，small intestine，lung，brain and kidney，but weakly expressed in spleen and bone marrow.After binding its ligand RANKL，RANK can activate signaling pathways such as NF-κB，JNK，ERK，p38，and Akt/PKB，through TRAF protein phosphorylation.RANK/TNFRSF11A signaling is largely considered to be growth promoting and apoptosis reducing such as the effects observed in osteoclasts.RANK/TNFRSF11A was also found to be involved in the regulation of interactions between T-cells and dendritic cells. |
| 来源 | Human Cells |
| 溶剂 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
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文献和实验的关系理不出头绪。GSK-3 beta 总蛋白减少，p-GSK-3 beta (ser 9)增加，是不是足以说明有活性的GSK-3 beta 减少更多，这样理解不知道对不对，希望给以指点。 galaxy22 楼主你好，请问你做出结果的tyr216的抗体是哪个公司的。。。我做出来总量是减少的，active B catenin是减少的，那我有必要做ser9 和tyr216的磷酸化形式吗？我想研究wnt和akt。。。 棉花糖的温柔
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,or write to the author. Identification of Tissue-Specific MicroRNAs from Mouse http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6VRT-45X0D1F-N&_user=440026&_coverDate=04%2F30%2F2002&_rdoc=1&_fmt=high&_orig=search&_sort=d&_docanchor=&view=c
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