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- 详细信息
- 文献和实验
- 技术资料
- 库存:
现询
- 供应商:
北京索莱宝科技有限公司
- 规格:
1mg/500ug/50ug/10ug
| 规格: | 1mg | 产品价格: | ¥21120.0 |
|---|---|---|---|
| 规格: | 500ug | 产品价格: | ¥14784.0 |
| 规格: | 50ug | 产品价格: | ¥2600.0 |
| 规格: | 10ug | 产品价格: | ¥936.0 |
| 基本信息 | |
| 基因名 | |
| 别名 | Artemin;ARTN;Enovin;Neublastin;EVN |
| 外观(性状) | Lyophilized from a 0.2 μm filtered solution of 20mM HEPES, 150mM NaCl, pH7.4. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 运输条件 | The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| 背景说明 | Human Artemin is a GDNF family ligand that is distantly related to the TGF-β superfamily of molecules.It is synthesized as a preproprotein,and contains a variable length pre-,or signal sequence,plus a 68 amino acid (aa) proregion and a 113 aa mature segment.Following synthesis and proteolytic processing,mature ARTN is secreted as a presumably glycosylated,28 kDa disulfide-linked homodimer that contains three intrachain disulfide bonds and the typical TGF-β signature cysteine-knot motif.In the mature region,human ARTN is 89% and 88% aa identical to rat and mouse ARTN,respectively.Human ARTN is active on rodent cells.The receptor for ARTN has been identified as the ligand binding subunit GFRα-3 plus the signal transducing subunit,RET.The GFRα-1/RET receptor complex has also been suggested to be a ligand binding unit for ARTN.ARTN is known to be a chemoattractant for sympathetic neuron axons innervating the developing cardiovascular system.It also promotes sensory neuron survival and likely plays a role in the development of the peripheral nervous system.Finally,it has been reported to reverse neuropathic pain due to nerve injury,and to help resolve morphological changes associated with nerve damage. |
| 来源 | E.coli |
| 溶剂 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
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