P01094 Recombinant Mouse SIRP alpha/CD172a/SIRPA/Signal-Regulatory Protein α-1 细胞因子/蛋白

P01094 Recombinant Mouse SIRP

alpha/CD172a/SIRPA/Signal-Regulatory Protein α-1 细胞因子/蛋白
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  • ¥988 - 21120
  • Solarbio已认证
  • P01094
  • 北京
  • 2025年07月25日
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    • 详细信息
    • 技术资料
    • 库存

      现询

    • 供应商

      北京索莱宝科技有限公司

    • 规格

      1mg/500ug/50ug/10ug

    规格:1mg产品价格:¥21120.0
    规格:500ug产品价格:¥14784.0
    规格:50ug产品价格:¥2600.0
    规格:10ug产品价格:¥988.0
    基本信息
    基因名
    别名Tyrosine-Protein Phosphatase Non-Receptor Type Substrate 1;CD172 Antigen-Like Family Member A;Signal-Regulatory Protein Alpha-1;CD172a;SIRPA;MFR;SHPS1;SIRP
    外观(性状)Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
    纯度≥95% as determined by reducing SDS-PAGE.
    储存条件Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
    运输条件The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below.
    背景说明SIRPα is a type I transmembrane glycoprotein.It contains two Ig-like C1-type domains and one Ig-like V-type domain.Mouse SIRP alpha ECD shares 61%,75%,62%,61%,and 59% aa sequence identity with human,rat,equine,bovine,and porcine SIRP alpha,respectively.SIRPα can express in various tissues,mainly on brain and myeloid cells,including macrophages,neutrophils,dendritic and Langerhans cells.It also can detect in neurons,smooth muscle and endothelial cells.SIRPA is an immunoglobulin-like cell surface receptor for CD47.SIRPα acts as docking protein and induces translocation of PTPN6,PTPN11 and other binding partners from the cytosol to the plasma membrane.SIRPα shows adhesion of cerebellar neurons,neurite outgrowth and glial cell attachment.SIRPα engagement generally produces a negative regulatory signal; it may mediate negative regulation of phagocytosis,mast cell activation and dendritic cell activation.
    来源Human Cells
    溶剂Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    内毒素Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.
    单位

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    ¥988 - 21120