- ￥988 - 21120
- Solarbio
- P01070
- 北京
- 2025年07月25日
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- 详细信息
- 文献和实验
- 技术资料
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 规格：
1mg/500ug/50ug/10ug
| 规格： | 1mg | 产品价格： | ￥21120.0 |
|---|---|---|---|
| 规格： | 500ug | 产品价格： | ￥14784.0 |
| 规格： | 50ug | 产品价格： | ￥2600.0 |
| 规格： | 10ug | 产品价格： | ￥988.0 |
| 基本信息 | |
| 基因名 | |
| 别名 | T-Cell Surface Glycoprotein CD3 Epsilon Chain;T-Cell Surface Antigen T3/Leu-4 Epsilon Chain;CD3e;CD3E;T3E |
| 外观(性状) | Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 运输条件 | The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| 背景说明 | T-Cell Surface Glycoprotein CD3 ε Chain (CD3ε) is a single-pass type I membrane protein.CD3ε contains 1 Ig-like (immunoglobulin-like) domain and 1 ITAM domain.CD3ε is a polypeptide encoded by the CD3E gene on chromosome 11 in humans.The T cell receptor-CD3 complex (TCR/CD3 complex) is involved in T-cell development and several intracellular signal-transduction pathways.This complex is critical for T-cell development and function，and represents one of the most complex transmembrane receptors.The T cell receptor-CD3 complex is unique in having ten cytoplasmic immunoreceptor tyrosine-based activation motifs (ITAMs).TCR/CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. |
| 来源 | Human Cells |
| 溶剂 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
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文献和实验T-Cell Activation Using mAb to CD3
splenic T-cells and human peripheral T cells stimulated via CD3. Critical parameters include cell density, antibody titer and activation kinetics. Materials 1X sterile PBS Anti-mouse CD3e, Clone 145-2C11 (Functional Grade, Cat. No. 16
盘点 2020 年中国学者的十大免疫学研究成果，有的已经被写进高考题？！
的远处转移的形成，表明 CCDC25 可能作为治疗肿瘤转移的潜在靶点。 7. 「续航更久，排放更低」，CAR-T 细胞治疗的继续革新！2020 年 7 月 30 日，中科院分子细胞科学卓越创新中心许琛琦团队，北京大学医学部黄超兰团队以及加州大学圣地亚哥分校的惠恩夫团队在 Cell 上合作发表了题为 Multiple Signaling Roles of CD3ε and Its Application in CAR-T Cell Therapy 的研究论文 (7)。该研究从 T 细胞信号转导的基础
.， Lai Z.Z.， Fan D.M.， Yang M.， Han J.L.， Xie Y.， Yang C.Z.， Zhu Z.P. Efficient inhibition of human B-cell lymphoma xenografts with an anti-CD20╳anti-CD3 bispecific diabody. Cancer Letter， 2002，177：29-39.
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