- ￥988 - 21120
- Solarbio
- P01062
- 北京
- 2025年07月25日
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- 详细信息
- 文献和实验
- 技术资料
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 规格：
1mg/500ug/50ug/10ug
| 规格： | 1mg | 产品价格： | ￥21120.0 |
|---|---|---|---|
| 规格： | 500ug | 产品价格： | ￥14784.0 |
| 规格： | 50ug | 产品价格： | ￥2600.0 |
| 规格： | 10ug | 产品价格： | ￥988.0 |
| 基本信息 | |
| 基因名 | |
| 别名 | Tumor necrosis factor receptor superfamily member 1A;TNFRSF1A;Tumor necrosis factor receptor 1;TNF-R1;TNF-RI;p55;p60;CD120a;TNFAR;TNFR1 |
| 外观(性状) | Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 运输条件 | The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| 背景说明 | Tumor necrosis factor receptor superfamily member 1A (TNFRSF1A) is a member of the tumor necrosis factor receptor superfamily.TNFRSF1A is one of the major receptors for the tumor necrosis factor-alpha.It can activate the transcription factor NF-κB，mediate apoptosis，and function as a regulator of inflammation.Antiapoptotic protein BCL2-associated athanogene 4 (BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown to interact with this receptor，and thus play regulatory roles in the signal transduction mediated by the receptor.Germline mutations of the extracellular domains of this receptor were found to be associated with the human genetic disorder called tumor necrosis factor associated periodic syndrome (TRAPS) or periodic fever syndrome. |
| 来源 | Human Cells |
| 溶剂 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
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文献和实验Production and Characterization of Recombinant Human and Murine TNF
Here we describe the methods for the expression of human and murine soluble tumor necrosis factor (hTNF and mTNF) in Escherichia coli cells and for their extraction, purification, and characterization. The expression and purification procedure
Tumor necrosis factor-α (TNF-α) is a cytokine (CK) that possesses a wide variety of biological activities, including potent antitumor activities (1 ) and immunomodulatory properties mediated through its binding to two TNF receptors (p55
TRAF‐Mediated TNFR‐Family Signaling
Pype, S., Declercq, W., Ibrahimi, A., Michiels, C., Van Rietschoten, J.G., Dewulf, N., de Boer, M., Vandenabeele, P., Huylebroeck, D., and Remacle, J.E. 2000. TTRAP, a novel protein that associates with CD40, tumor necrosis factor (TNF
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