P01045 Recombinant Mouse SLAMF5/SLAM Family Member 5/CD84 细胞因子/蛋白

P01045 Recombinant Mouse SLAMF

5/SLAM Family Member 5/CD84 细胞因子/蛋白
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  • ¥988 - 21120
  • Solarbio已认证
  • P01045
  • 北京
  • 2025年07月25日
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    • 详细信息
    • 技术资料
    • 库存

      现询

    • 供应商

      北京索莱宝科技有限公司

    • 规格

      1mg/500ug/50ug/10ug

    规格:1mg产品价格:¥21120.0
    规格:500ug产品价格:¥14784.0
    规格:50ug产品价格:¥2600.0
    规格:10ug产品价格:¥988.0
    基本信息
    基因名
    别名SLAM family member 5;Cd84;Leukocyte differentiation antigen CD84;Signaling lymphocytic activation molecule 5;CD84;Ly-9B;SLAMF5;CD84 antigen;CD84 molecule;SLAM family member 5
    外观(性状)Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    纯度≥95% as determined by reducing SDS-PAGE.
    储存条件Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
    运输条件The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below.
    背景说明CD84,also called SLAMF5,is a member of the CD2 subgroup of the immunoglobulin receptor superfamily.Members of this CD2 subgroup mediate signal transduction through the interaction of its immunoreceptor tyrosine-based switch motifs (ITSM) in the intracellular region and the SH2 domain of adaptor molecules SAP (SLAM-associated protein) and EAT-2 (EWS-activated transcript 2),and accordingly modulate both adaptive and innate immune responses.CD84 expression has been documented on several hematopoietic cell types,including monocytes,macrophages,dendritic cells,B lymphocytes,and platelets.Activation of cell surface CD84 initiates a signaling cascade involving its intra-cytoplasmic tyrosine residues that results in Bcl-2 upregulation,which in turn enhances cell survival.Either immunoneutralization or blockade of CD84 with a CD84 extracellular domain protein fragment induces cell death in vitro and in vivo.
    来源Human Cells
    溶剂Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    内毒素Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.
    单位

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    ¥988 - 21120