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- Solarbio
- P00861
- 北京
- 2025年07月25日
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- 详细信息
- 文献和实验
- 技术资料
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 规格：
1mg/500ug/50ug/10ug
| 规格： | 1mg | 产品价格： | ￥15360.0 |
|---|---|---|---|
| 规格： | 500ug | 产品价格： | ￥10752.0 |
| 规格： | 50ug | 产品价格： | ￥2600.0 |
| 规格： | 10ug | 产品价格： | ￥936.0 |
| 基本信息 | |
| 基因名 | |
| 别名 | T-lymphocyte surface antigen Ly-9;Cell surface molecule Ly-9;Lymphocyte antigen 9;SLAM family member 3;SLAMF3;Signaling lymphocytic activation molecule 3;CD229;Ly9;Ly-9 |
| 外观(性状) | Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 运输条件 | The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| 背景说明 | CD229(SLAMF3) is a type I transmembrane glycoprotein in the SLAM subgroup of the CD2 family.Mature mouse CD229 consists of a 406 aa extracellular domain (ECD) with two Ig-like V-set and two Ig-like truncated C2-set domains，a 21 aa transmembrane segment，and a 180 aa cytoplasmic domain with two immunoreceptor tyrosinebased switch motifs ITSMs.Within the first two Ig-like domains that are common to all SLAM proteins，mouse CD229 shares 22%-36% aa sequence identity with mouse 2B4，BLAME，CD2F10，CD84，CRACC，NTBA，and SLAM.CD229 is expressed on T，B，and NK cells，thymocytes and monocytes.Homophilic binding between CD229 molecules is mediated by the N-terminal Ig-like domain.Human and mouse CD229 exhibit crossspecies binding.Antigen stimulation of lymphocytes induces CD229 clustering to sites of T cell-B cell contact.Antibody ligation of CD229 can inhibit T cell activation，but CD229 knockout mice show impaired T cell immune responses，suggesting a potential role for CD229 in T cell activation or costimulation. |
| 来源 | Human Cells |
| 溶剂 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
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文献和实验Isolation of Human Tumor-Associated Cell Surface Antigen-Binding scFvs
has been successfully used to identify TAA recognized by mouse monoclonal Abs (for review, see ref. 1 ). The SEREX methodology, i.e., serological analysis of recombinant cDNA expression libraries prepared from malignant cells, has also been successfully used to identify
Using Biacore to Measure the Binding Kinetics of an Antibody‐Antigen Interaction
‐globulin in HBS‐P+ (see recipe for HBS‐P+) 10 mM glycine, pH 1.5, 2.0, 2.5, and 3.0 Biacore 3000, 2000, or T
randomly paired light (L) and heavy (H) chain coding regions under transcriptional control of P lac . The H chain coding region is fused in-frame with the phage gene, Δ gIII , coding for a truncated version of the phage surface protein pIII (ΔpIII
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