P01035 Recombinant Human ULBP1/RAET1/N2DL1 细胞因子/蛋白

P01035 Recombinant Human ULBP1

/RAET1/N2DL1 细胞因子/蛋白
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  • ¥988 - 21120
  • Solarbio已认证
  • P01035
  • 北京
  • 2025年07月25日
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    • 详细信息
    • 技术资料
    • 库存

      现询

    • 供应商

      北京索莱宝科技有限公司

    • 规格

      1mg/500ug/50ug/10ug

    规格:1mg产品价格:¥21120.0
    规格:500ug产品价格:¥14784.0
    规格:50ug产品价格:¥2600.0
    规格:10ug产品价格:¥988.0
    基本信息
    基因名
    别名NKG2D ligand 1;NKG2DL1;ALCAN-beta;Retinoic acid early transcript 1I;UL16-binding protein 1;ULBP1
    外观(性状)Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
    纯度≥95% as determined by reducing SDS-PAGE.
    储存条件Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
    运输条件The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below.
    背景说明NKG2D ligand 1,also called ULBP1,is a member of UL16-binding protein (ULBP) family which has also been termed the retinoic acid early transcript 1 (RAET1) family.Unlike the classical MHC class I molecules and the MIC molecules possess α1,α2 and α3 domains,ULBP/RAET1 family members lack α3 domain.ULBP1 is recognized by the activating receptor NKG2D on the surface of cytotoxic natural killer (NK) and T cells,and then promotes the lysis of cells expressing ULBP1 which is important for the immune surveillance.ULBP1 and several other family members,ULBP2 and ULBP5,own the ability to bind the human cytomegalovirus (CMV) UL16 glycoprotein.The human CMV glycoprotein UL16 binds to intracellular ULBP1 and so inhibits its expression at the cell surface,which reduces the susceptibility of the virus-infected cell to cytotoxic destruction by NK cells.The expression of ULBP1 has been found on some tumor cells and is implicated in tumor surveillance.
    来源Human Cells
    溶剂Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    内毒素Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.
    单位

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    P01035 Recombinant Human ULBP1/RAET1/N2DL1 细胞因子/蛋白
    ¥988 - 21120