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- 库存:
现询
- 供应商:
北京索莱宝科技有限公司
- 规格:
1mg/500ug/50ug/10ug
| 规格: | 1mg | 产品价格: | ¥15360.0 |
|---|---|---|---|
| 规格: | 500ug | 产品价格: | ¥10752.0 |
| 规格: | 50ug | 产品价格: | ¥2600.0 |
| 规格: | 10ug | 产品价格: | ¥988.0 |
| 基本信息 | |
| 基因名 | |
| 别名 | Apoptosis regulator Bcl-2;BCL2 |
| 外观(性状) | Supplied as a 0.2 μm filtered solution of 20mM HEPES, 150mM NaCl, 10%Glycerol, pH8.0. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Store at≤-70℃,6 months.with seal;3 month after opening.Avoid freeze/thaw cycles. |
| 运输条件 | 干冰运输 |
| 背景说明 | Bcl-2 is a member of a family of proteins that regulates outer mitochondrial membrane permeability.Bcl-2 is an antiapoptotic member that prevents release of cytochrome c from the mitochondria intermembrane space into the cytosol.Bcl-2 is present on the outer mitochondrial membrane and is also found on other membranes in some cell types.BCL-2 is localized to the outer membrane of mitochondria,where it plays an important role in promoting cellular survival and inhibiting the actions of pro-apoptotic proteins.The pro-apoptotic proteins in the BCL-2 family,including Bax and Bak,normally act on the mitochondrial membrane to promote permeabilization and release of cytochrome C and ROS,that are important signals in the apotosis cascade.These pro-apoptotic proteins are in turn activated by BH3-only proteins,and are inhibited by the function of BCL-2 and its relative BCL-Xl. |
| 来源 | E.coli |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
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文献和实验【分享】Human press METHODS IN MOLECULAR BIOLOGY
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浅析染色质免疫沉淀(ChIP)技术在 DNA 与蛋白质相互作用研究中的重要性
, B.E., et al., A bivalent chromatin structure marks key developmental genes in embryonic stem cells. Cell, 2006. 125(2): p. 315-26. [19] Topp, C.N., C.X. Zhong, and R.K. Dawe, Centromere-encoded RNAs are integral components of the maize kinetochore
TRAF‐Mediated TNFR‐Family Signaling
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