P00975 Recombinant Human Apoptosis Regulator Bcl-2/B-cell Lymphoma 2 细胞因子/蛋白

P00975 Recombinant Human Apopt

osis Regulator Bcl-2/B-cell Lymphoma 2 细胞因子/蛋白
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  • ¥988 - 15360
  • Solarbio已认证
  • P00975
  • 北京
  • 2025年07月25日
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    • 详细信息
    • 技术资料
    • 库存

      现询

    • 供应商

      北京索莱宝科技有限公司

    • 规格

      1mg/500ug/50ug/10ug

    规格:1mg产品价格:¥15360.0
    规格:500ug产品价格:¥10752.0
    规格:50ug产品价格:¥2600.0
    规格:10ug产品价格:¥988.0
    基本信息
    基因名
    别名Apoptosis regulator Bcl-2;BCL2
    外观(性状)Supplied as a 0.2 μm filtered solution of 20mM HEPES, 150mM NaCl, 10%Glycerol, pH8.0.
    纯度≥95% as determined by reducing SDS-PAGE.
    储存条件Store at≤-70℃,6 months.with seal;3 month after opening.Avoid freeze/thaw cycles.
    运输条件干冰运输
    背景说明Bcl-2 is a member of a family of proteins that regulates outer mitochondrial membrane permeability.Bcl-2 is an antiapoptotic member that prevents release of cytochrome c from the mitochondria intermembrane space into the cytosol.Bcl-2 is present on the outer mitochondrial membrane and is also found on other membranes in some cell types.BCL-2 is localized to the outer membrane of mitochondria,where it plays an important role in promoting cellular survival and inhibiting the actions of pro-apoptotic proteins.The pro-apoptotic proteins in the BCL-2 family,including Bax and Bak,normally act on the mitochondrial membrane to promote permeabilization and release of cytochrome C and ROS,that are important signals in the apotosis cascade.These pro-apoptotic proteins are in turn activated by BH3-only proteins,and are inhibited by the function of BCL-2 and its relative BCL-Xl.
    来源E.coli
    内毒素Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.
    单位

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