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- 库存:
现询
- 供应商:
北京索莱宝科技有限公司
- 规格:
1mg/500ug/50ug/10ug
| 规格: | 1mg | 产品价格: | ¥21120.0 |
|---|---|---|---|
| 规格: | 500ug | 产品价格: | ¥14784.0 |
| 规格: | 50ug | 产品价格: | ¥3276.0 |
| 规格: | 10ug | 产品价格: | ¥1092.0 |
| 基本信息 | |
| 基因名 | |
| 别名 | Carboxypeptidase B2;Carboxypeptidase U;CPU;Plasma Carboxypeptidase B;pCPB;Thrombin-Activable Fibrinolysis Inhibitor;TAFI;CPB2 |
| 外观(性状) | Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl,150mM NaCl,1mM ZnCl2,10%Glycerol, pH7.5. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
| 运输条件 | 干冰运输 |
| 背景说明 | Carboxypeptidase B2 (CPB2) is a secreted enzyme that belongs to the peptidase M14 family.CPB2 is synthesized by the liver and circulates in the plasma as a plasminogen-bound zymogen by the liver and circulates in the plasma as a plasminogen-bound zymogen.CPB2 cleaves C-terminal arginine or lysine residues from biologically active peptides,such as kinins or anaphylatoxins,in the circulation regulating their activities.CPB2 also down-regulates fibrinolysis by removing C-terminal lysine residues from fibrin that has already been partially degraded by plasmin.CPB2 exhibits carboxypeptidase activity when it is activated by proteolysis at residue Arg92 of the thrombin/thrombomodulin complex.Activated CPB2 reduces fibrinolysis by removing the fibrin C-terminal residues that are important for the binding and activation of plasminogen. |
| 来源 | Human Cells |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
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