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- 详细信息
- 文献和实验
- 技术资料
- 库存:
现询
- 供应商:
北京索莱宝科技有限公司
- 规格:
1mg/500ug/50ug/10ug
| 规格: | 1mg | 产品价格: | ¥21120.0 |
|---|---|---|---|
| 规格: | 500ug | 产品价格: | ¥14784.0 |
| 规格: | 50ug | 产品价格: | ¥2964.0 |
| 规格: | 10ug | 产品价格: | ¥988.0 |
| 基本信息 | |
| 基因名 | |
| 别名 | Guanidinoacetate N-methyltransferase;GAMT;PIG2;TP53I2 |
| 外观(性状) | Supplied as a 0.2 μm filtered solution of 20mM TrisHCl,1mMDTT,pH 8.0 . |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
| 运输条件 | 干冰运输 |
| 背景说明 | GAMT is a methyltransferase which belongs to the class I-like SAM-binding methyltransferase superfamily.It contains one RMT2 (arginine N-methyltransferase 2-like) domain and is expressed in liver.GAMT converts guanidoacetate to creatine,using S-adenosylmethionine as the methyl donor.Defects in GAMT are the cause of guanidinoacetate methyltransferase deficiency,which is an autosomal recessive disorder characterized by developmental delay/regression,mental retardation,severe disturbance of expressive and cognitive speech,intractable seizures and movement disturbances,severe depletion of creatine/phosphocreatine in the brain,and accumulation of guanidinoacetic acid in brain and body fluids. |
| 来源 | E.coli |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
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