P00896 Recombinant Cynomolgus PD-L1/B7-H1/CD274/Programmed Cell Death 1 Ligand 1 细胞因子/蛋白

P00896 Recombinant Cynomolgus

PD-L1/B7-H1/CD274/Programmed Cell Death 1 Ligand 1 细胞因子/蛋白
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  • ¥936 - 17280
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  • P00896
  • 北京
  • 2025年07月25日
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    • 详细信息
    • 技术资料
    • 库存

      现询

    • 供应商

      北京索莱宝科技有限公司

    • 规格

      1mg/500ug/50ug/10ug

    规格:1mg产品价格:¥17280.0
    规格:500ug产品价格:¥12096.0
    规格:50ug产品价格:¥2600.0
    规格:10ug产品价格:¥936.0
    基本信息
    基因名
    别名B7-H;B7H1;B7-H1;B7H1PDCD1L1;CD274 antigenMGC142294;CD274 molecule;CD274;PDCD1L1;PDCD1LG1;PDL1;PD-L1;PD-L1B7 homolog 1;PDL1PDCD1 ligand 1;programmed cell death 1 ligand 1;Programmed death ligand 1
    外观(性状)Lyophilized from a 0.2 μm filtered solution of PBS,pH 7.4.
    纯度≥95% as determined by reducing SDS-PAGE.
    储存条件Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
    运输条件The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below.
    背景说明CD274,also known as B7-H1 or programmed death ligand 1 (PD-L1),is a 40 kD type I transmembrane protein and a member of the B7 family within the immunoglobulin receptor superfamily.Programmed death-1 ligand-1 (PD-L1,CD274,B7-H1) has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune responses and peripheral tolerance.By binding to PD1 on activated T-cells and B-cells,PD-L1 may inhibit ongoing T-cell responses by inducing apoptosis and arresting cell-cycle progression.Accordingly,it leads to growth of immunogenic tumor growth by increasing apoptosis of antigen specific T cells and may contribute to immune evasion by cancers.PD-L1 thus is regarded as promising therapeutic target for human autoimmune disease and malignant cancers.
    来源Human Cells
    溶剂Dissolve the lyophilized protein in distilled water.
    内毒素Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.
    单位

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    P00896 Recombinant Cynomolgus PD-L1/B7-H1/CD274/Programmed Cell Death 1 Ligand 1 细胞因子/蛋白
    ¥936 - 17280