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- 详细信息
- 文献和实验
- 技术资料
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 规格：
1mg/500ug/50ug/10ug
| 规格： | 1mg | 产品价格： | ￥15360.0 |
|---|---|---|---|
| 规格： | 500ug | 产品价格： | ￥10752.0 |
| 规格： | 50ug | 产品价格： | ￥2600.0 |
| 规格： | 10ug | 产品价格： | ￥936.0 |
| 基本信息 | |
| 基因名 | |
| 别名 | P-selectin glycoprotein ligand 1;PSGL-1;Selectin P ligand;CD162;SELPLG |
| 外观(性状) | Lyophilized from a 0.2 μm filtered solution of 20mM Tris,150mM NaCl,pH8.0. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 运输条件 | The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| 背景说明 | PSGL-1 (CD162)，is a mucintype glycoprotein that plays a key role in leukocyte adhesion.Human PSGL-1 cDNA encodes 412 amino acids (aa).It expressed on neutrophils，monocytes and most lymphocytes.The mature PSGL-1 (aa 42-412) is expressed as a disulfide-linked homodimer that signals intracellularly and promotes integrin activation.PSGL-1 is found on virtually all leukocytes，dendritic cells，platelets，and some endothelial cells.It is primarily responsible for early events in extravasation，especially rolling adhesion of leukocytes to vascular endothelium.Through high affinity，This SLe(x)-type proteoglycanPGSL-1 calcium-dependent interactions with E-，P- and L-selectins，mediates rapid rolling of leukocytes over vascular surfaces during the initial steps in inflammation. |
| 来源 | Human Cells |
| 溶剂 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
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文献和实验Ligand Characterization Using Microphysiometry
., and Pitchford, S. 1994. Recombinant human ciliary neurotrophic factor stimulates metabolic activity of SH‐SY5Y cells as measured by a Cytosensor microphysiometer. Brain Res. 646:327‐331.
Preparation of recombinant fibronectin fragments for functional and structural studies
integrin receptors. The mosaic nature of fibronectin permits it to be analyzed by a “dissection” strategy, where protein fragments generated by recombinant expression in E. coli , P. pastoris , and human cell lines are employed in structural and functional
Introduction of human 14-3-3 proteins
----------------------------------------------------------------------------A binding sequence for the 14-3-3 protein within the cytoplasmic domain of the adhesion receptor,platelet glycoprotein Ib alphaDu X; Fox JE; Pei SDepartment of Vascular Biology,Scripps Research Institute,La Jolla,California
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