P00872 Recombinant Human T-cell Immunoglobulin and Mucin Domain-containing Protein 4/Tim-4 细胞因子/蛋白

P00872 Recombinant Human T-cel

l Immunoglobulin and Mucin Domain-containing Protein 4/Tim-4 细胞因子/蛋白
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  • ¥936 - 15360
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  • P00872
  • 北京
  • 2025年07月25日
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    • 详细信息
    • 技术资料
    • 库存

      现询

    • 供应商

      北京索莱宝科技有限公司

    • 规格

      1mg/500ug/50ug/10ug

    规格:1mg产品价格:¥15360.0
    规格:500ug产品价格:¥10752.0
    规格:50ug产品价格:¥2600.0
    规格:10ug产品价格:¥936.0
    基本信息
    基因名
    别名T-cell immunoglobulin and mucin domain-containing protein 4;TIMD-4;T-cell immunoglobulin mucin receptor 4;TIM-4;T-cell membrane protein 4;TIMD4;TIM4
    外观(性状)Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
    纯度≥95% as determined by reducing SDS-PAGE.
    储存条件Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
    运输条件The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below.
    背景说明T-cell Immunoglobulin and Mucin Domain-containing Protein 4(TIM-4) belongs to the immunoglobulin superfamily,is a member of the TIM family of immune regulating proteins.TIMs are type I transmembrane proteins with one Ig-like V domain and one Ser/Thr-rich mucin domain.Structurally,TIM-4 is distinguished from other TIMs by the presence of an RGD motif in its Ig domain and the lack of a site for tyrosine phosphorylation in its cytoplasmic tail.The mucin domain in TIM-4 is larger than in TIM-1 or TIM-3.TIM-4 is expressed by macrophages and mature dendritic cells but not by lymphocytes.it is Involved in regulating T-cell proliferation and lymphotoxin signaling.The interaction of TIM-4 with TIM-1 induces costimulatory and hyperproliferative signals in T cells.TIM-4 binds specifically to TIM-1 which is also the cellular receptor for the hepatitis A virus,and has been implicated in the development of asthma.
    来源Human Cells
    溶剂Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    内毒素Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.
    单位

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