P00201 Recombinant Human IL-1

Recombinant Human Interleukin-12 receptor subunit beta-1 is produced by our Mammalian expression system and the target gene encoding Cys24-Glu540 is expressed with a Fc tag at the C-terminus.

基本信息
基因名
别名	CD212;IL12RB1;CD212;CD212 antigen;IL-12 receptor beta component;IL-12 receptor subunit beta-1;IL12R;IL-12R subunit beta-1;IL12RB;IL-12RB1;IL-12R-BETA1;IL-12R-beta-1;interleukin-12 receptor beta-1 chain;interleukin-12 receptor subunit beta-1
外观(性状)	Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
纯度	≥95% as determined by reducing SDS-PAGE.
储存条件	Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
运输条件	The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below.
背景说明	Interleukin12 receptor subunit beta 1 (IL12RB1) is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily.IL12RB1 can spontaneously form homodimers and -oligomers，which are able to bind IL12 with only low affinity.IL12 high affinity receptor complex is composed of two subunits designated IL12RB1 and IL12RB2.While IL12RB1 interacts with the IL-12p40 subunit，IL-12p35 is mainly connecting with IL12RB2.This receptor chain is also responsible for transmitting the IL12 signal into the cell.IL12RB1，to the contrary，is also part of the IL23R，where it interacts with the p40 subunit of IL23.IL12RB1 is expressed in activated T cells，NK cells and B cells.
来源	Human cells
溶剂	Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素	Less than 0.1 ng/ug(1 IEU/ug)as determined by LAL test.
单位	支