- ￥936 - 17280
- Solarbio
- P00864
- 北京
- 2025年07月25日
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￥936
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- 详细信息
- 文献和实验
- 技术资料
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 规格：
1mg/500ug/50ug/10ug
| 规格： | 1mg | 产品价格： | ￥17280.0 |
|---|---|---|---|
| 规格： | 500ug | 产品价格： | ￥12096.0 |
| 规格： | 50ug | 产品价格： | ￥2600.0 |
| 规格： | 10ug | 产品价格： | ￥936.0 |
| 基本信息 | |
| 基因名 | |
| 别名 | T-cell surface glycoprotein CD4;T-cell surface antigen T4/Leu-3;CD4;Scd4 |
| 外观(性状) | Lyophilized from a 0.2 μm filtered solution of PBS,1mM EDTA,PH7.4. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 运输条件 | The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| 背景说明 | CD4 is an approximately 55 kDa type-I transmembrane glycoprotein that is expressed predominantly on thymocytes and a subset of mature T-lymphocytes.It is a standard phenotype marker for the identification of T-cell populations.Mature human CD4 consists of a 371 amino acid extracellular region containing four immunoglobulin-like domains，a 22 aa transmembrane segment，and a 40 aa cytoplasmic domain.CD4 is expressed along with CD8 on double positive T-cells during their development in the thymus.CD4 binds directly to MHC class-II molecules on antigen presenting cells (10).This interaction contributes to the formation of the immunological synapse which is focused around the TCR-MHC class II-antigenic peptide interaction.CD4 also functions as a chemotactic receptor for IL-16 and，in human，as a co-receptor for the gp120 surface glycoprotein of HIV-1. |
| 来源 | Human Cells |
| 溶剂 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
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文献和实验Fusion mediated by the human immunodeficiency virus type-1 (HIV-1) envelope (Env) glycoprotein and the cellular CD4/chemokine receptor complex is the first step in entry and is often analyzed in cell-cell fusion assays that require Env expression
Characterization of HIV gp120 Envelope Glycoprotein by Lectin Analysis
The envelope glycoprotein gp120 of the human immunodeficiency virus (HIV), the causative agent of AIDS, contains approx 24 potential sites for N -glycosylation (Asn-X-Ser/Thr, X≠Pro) (1 ), all of which are utilized
Hematopoietic Stem Cell Targeting with Surface-Engineered Lentiviral Vectors
Hematopoietic Stem Cell Targeting with Surface-Engineered Lentiviral Vectors Els Verhoeyen and François-Loïc Cosset Adapted from Gene Transfer: Delivery and Expression of DNA and RNA (eds. Friedmann and Rossi). CSHL Press, Cold
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