- ￥936 - 21120
- Solarbio
- P00847
- 北京
- 2025年07月25日
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- 详细信息
- 文献和实验
- 技术资料
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 规格：
1mg/500ug/50ug/10ug
| 规格： | 1mg | 产品价格： | ￥21120.0 |
|---|---|---|---|
| 规格： | 500ug | 产品价格： | ￥14784.0 |
| 规格： | 50ug | 产品价格： | ￥2600.0 |
| 规格： | 10ug | 产品价格： | ￥936.0 |
| 基本信息 | |
| 基因名 | |
| 别名 | SLAM family member 6;Activating NK receptor;NK-T-B-antigen;NTB-A;CD352;SLAMF6;KALI |
| 外观(性状) | Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 运输条件 | The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| 背景说明 | SLAM Family Member 6 (SLAMF6) is a single-pass type I membrane protein that belongs to the SLAM subgroup of the CD2 family.Human SLAMF6/ NTB-A contains a 205 amino acid extracellular domain (ECD) with one Ig-like V-set and one Ig-like C2-set domain，a 21 amino acid transmembrane segment and an 84 amino acid cytoplasmic domain，with two immunoreceptor tyrosine-based switch motifs.SLAMF6 is a homodimer.SLAMF6 can interact with PTN6 and，upon phosphorylation，with PTN11 and SH2D1A/SAP.Phosphorylation-dependent NTB-A association with SAP is required for full production of IFN-γ by NK cells and independent of EAT-2 binding.It Triggers cytolytic activity only in natural killer cells (NK) expressing high surface densities of natural cytotoxicity receptors.On B cells，NTB-A modulates immunoglobulin class switching and the balance between tolerance and autoimmunity. |
| 来源 | Human Cells |
| 溶剂 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
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文献和实验Mimic-Based RT-PCR Quantitation of Substance P mRNA in Human Mononuclear Phagocytes and Lymphocytes
Substance P (SP), the most extensively studied and most potent member of the tachykinin family, is a modulator in neuroimmunoregulation (1 –4 ). SP has been described as a peptide that is almost exclusively of neural origin
TRAF‐Mediated TNFR‐Family Signaling
, A.M., Dowd, A.D., Brush, A.D., Heldens, A.D., Schow, A.D., Goddard, A.D., Wood, W.I., Baker, K.P., Godowski, P.J., and Ashkenazi, A. 1999. Identification of a new member of the tumor necrosis factor family and its receptor, a human ortholog of mouse
CD11a/CD11b/CD11c 分子 CDlla 常用单克隆抗体或代号：MHM24， 2F12； CRIS―3(LFA―lα链，整合素α1) 主要表达细胞：Leu[A5] 分子质量(kDa)和结构：spl80(整合素α) 功 能：与1CAM-l(CD54)、ICAM-2(CDl02)、ICAM-3(C1350)结合，介导细胞黏附；与JAMl结合，参与白细胞穿过内皮细胞
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