P00841 Recombinant Human VEGF R1/Flt-1/FLT1 细胞因子/蛋白

P00841 Recombinant Human VEGF

R1/Flt-1/FLT1 细胞因子/蛋白
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  • ¥936 - 15360
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  • P00841
  • 北京
  • 2025年07月25日
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    • 详细信息
    • 技术资料
    • 库存

      现询

    • 供应商

      北京索莱宝科技有限公司

    • 规格

      1mg/500ug/50ug/10ug

    规格:1mg产品价格:¥15360.0
    规格:500ug产品价格:¥10080.0
    规格:50ug产品价格:¥2600.0
    规格:10ug产品价格:¥936.0
    基本信息
    基因名
    别名Vascular endothelial growth factor receptor 1;VEGFR-1;Fms-like tyrosine kinase 1;FLT-1;Tyrosine-protein kinase FRT;Tyrosine-protein kinase receptor FLT;Vascular permeability factor receptor
    外观(性状)Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    纯度≥95% as determined by reducing SDS-PAGE.
    储存条件Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
    运输条件The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below.
    背景说明Human Vascular endothelial growth factor receptor 1(VEGFR-1,FLT-1) is a member of the the class III subfamily of receptor tyrosine kinases (RTKs) and Tyr protein kinase family and CSF-1/PDGF receptor subfamily.VEGFR-1 is widely expressed in human tissues including normal lung,placenta,liver,kidney,heart and brain tissues.It is specifically expressed in most of the vascular endothelial cellsand peripheral blood monocytes.VEGFR-1 contains seven Ig-like C2-type domains and one protein kinase domain.VEGFR-1is an essential receptor tyrosine kinase and plays an important role in theregulation of VEGF family-mediated vasculogenesis,angiogenesis,and lymphangiogenesis.It is also mediators of neurotrophic activity and regulators of hematopoietic development.VEGFR-1 is a receptor for VEGF,VEGFB and PGF.It has a tyrosine-protein kinase activity.Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA,VEGFB and PGF.It may play an essential role as a negative regulator of embryonic angiogenesis by inhibiting excessive proliferation of endothelial cells and promote endothelial cell proliferation,survival and angiogenesis in adulthood.Its function in promoting cell proliferation seems to be cell-type specific.VEGFR-1 can also promote PGF-mediated proliferation of endothelial cells,proliferation of some types of cancer cells,but does not promote proliferation of normal fibroblasts (in vitro).
    来源Human Cells
    溶剂Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    内毒素Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.
    单位

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    P00841 Recombinant Human VEGF R1/Flt-1/FLT1 细胞因子/蛋白
    ¥936 - 15360