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- 详细信息
- 文献和实验
- 技术资料
- 库存:
现询
- 供应商:
北京索莱宝科技有限公司
- 规格:
1mg/500ug/50ug/10ug
| 规格: | 1mg | 产品价格: | ¥15360.0 |
|---|---|---|---|
| 规格: | 500ug | 产品价格: | ¥10080.0 |
| 规格: | 50ug | 产品价格: | ¥2600.0 |
| 规格: | 10ug | 产品价格: | ¥936.0 |
| 基本信息 | |
| 基因名 | |
| 别名 | Vascular endothelial growth factor receptor 1;VEGFR-1;Fms-like tyrosine kinase 1;FLT-1;Tyrosine-protein kinase FRT;Tyrosine-protein kinase receptor FLT;Vascular permeability factor receptor |
| 外观(性状) | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 运输条件 | The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| 背景说明 | Human Vascular endothelial growth factor receptor 1(VEGFR-1,FLT-1) is a member of the the class III subfamily of receptor tyrosine kinases (RTKs) and Tyr protein kinase family and CSF-1/PDGF receptor subfamily.VEGFR-1 is widely expressed in human tissues including normal lung,placenta,liver,kidney,heart and brain tissues.It is specifically expressed in most of the vascular endothelial cellsand peripheral blood monocytes.VEGFR-1 contains seven Ig-like C2-type domains and one protein kinase domain.VEGFR-1is an essential receptor tyrosine kinase and plays an important role in theregulation of VEGF family-mediated vasculogenesis,angiogenesis,and lymphangiogenesis.It is also mediators of neurotrophic activity and regulators of hematopoietic development.VEGFR-1 is a receptor for VEGF,VEGFB and PGF.It has a tyrosine-protein kinase activity.Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA,VEGFB and PGF.It may play an essential role as a negative regulator of embryonic angiogenesis by inhibiting excessive proliferation of endothelial cells and promote endothelial cell proliferation,survival and angiogenesis in adulthood.Its function in promoting cell proliferation seems to be cell-type specific.VEGFR-1 can also promote PGF-mediated proliferation of endothelial cells,proliferation of some types of cancer cells,but does not promote proliferation of normal fibroblasts (in vitro). |
| 来源 | Human Cells |
| 溶剂 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
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