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- 详细信息
- 技术资料
- 库存:
现询
- 供应商:
北京索莱宝科技有限公司
- 规格:
1mg/500ug/50ug/10ug
| 规格: | 1mg | 产品价格: | ¥17280.0 |
|---|---|---|---|
| 规格: | 500ug | 产品价格: | ¥12096.0 |
| 规格: | 50ug | 产品价格: | ¥2600.0 |
| 规格: | 10ug | 产品价格: | ¥936.0 |
| 基本信息 | |
| 基因名 | |
| 别名 | Hemopexin;Hpx;Hpxn |
| 中文名称 | Recombinant Human Hemopexin |
| 外观(性状) | Supplied as a 0.2 μm filtered solution of 20mM MES,150mM NaCl,pH5.5. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
| 运输条件 | 干冰运输 |
| 背景说明 | Hemopexin (HPX) is plasma glycoprotein belongs to the family of the acute-phase proteins whose synthesis is induced after an inflammatory event.Hemopexin with two four-bladed beta -propeller folds has been found in other proteins including collagenases and provides sites for protein-protein interactions.The liver is the major synthesizing organ.Hemopexin participates in maintaining and recycling the iron pool by utilizing its high binding affinity toward heme composed of protoporphyrin IX and iron.It also functions in preventing oxidation caused by heme after hemolysis.Hydrophobic heme molecules can intercalate into lipid membranes and participate in the oxidation of lipid membrane components through the Fenton reaction resulting in lipid peroxidation.Hemopexin undergoes a conformational change upon the binding of heme.The conformational change allows hemopexin to interact with a specific receptor,forming a complex which is then internalized.Heme concentrations in plasma increase after hemolysis,which is associated with several pathological conditions such as reperfusion injury and ischemia. |
| 来源 | Human Cells |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
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P00816 Recombinant Human Hemopexin 细胞因子/蛋白
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