P00815 Recombinant Mouse Hemopexin 细胞因子/蛋白

P00815 Recombinant Mouse Hemop

exin 细胞因子/蛋白
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  • ¥936 - 21120
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  • P00815
  • 北京
  • 2025年07月25日
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    • 详细信息
    • 技术资料
    • 库存

      现询

    • 供应商

      北京索莱宝科技有限公司

    • 规格

      1mg/500ug/50ug/10ug

    规格:1mg产品价格:¥21120.0
    规格:500ug产品价格:¥14784.0
    规格:50ug产品价格:¥2600.0
    规格:10ug产品价格:¥936.0
    基本信息
    基因名
    别名Hemopexin;Hpx;Hpxn
    中文名称Recombinant Mouse Hemopexin
    外观(性状)Supplied as a 0.2 μm filtered solution of 20mM MES, 150mM NaCl, pH 5.5.
    纯度≥95% as determined by reducing SDS-PAGE.
    储存条件Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.
    运输条件干冰运输
    背景说明Hemopexin (HPX) is plasma glycoprotein belongs to the family of the acute-phase proteins whose synthesis is induced after an inflammatory event.Hemopexin with two four-bladed beta -propeller folds has been found in other proteins including collagenases and provides sites for protein-protein interactions.The liver is the major synthesizing organ.Hemopexin participates in maintaining and recycling the iron pool by utilizing its high binding affinity toward heme composed of protoporphyrin IX and iron.It also functions in preventing oxidation caused by heme after hemolysis.Hydrophobic heme molecules can intercalate into lipid membranes and participate in the oxidation of lipid membrane components through the Fenton reaction resulting in lipid peroxidation.Hemopexin undergoes a conformational change upon the binding of heme.The conformational change allows hemopexin to interact with a specific receptor,forming a complex which is then internalized.Heme concentrations in plasma increase after hemolysis,which is associated with several pathological conditions such as reperfusion injury and ischemia.
    来源Human Cells
    内毒素Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.
    单位

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