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- P00813
- 北京
- 2025年07月25日
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- 详细信息
- 文献和实验
- 技术资料
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 规格：
1mg/500ug/50ug/10ug
| 规格： | 1mg | 产品价格： | ￥15360.0 |
|---|---|---|---|
| 规格： | 500ug | 产品价格： | ￥10752.0 |
| 规格： | 50ug | 产品价格： | ￥2600.0 |
| 规格： | 10ug | 产品价格： | ￥936.0 |
| 基本信息 | |
| 基因名 | |
| 别名 | Inositol monophosphatase 3;Impad1 |
| 中文名称 | Recombinant Mouse Inositol Monophosphatase 3/IMPAD1/IMP3/IMPA3 |
| 外观(性状) | Supplied as a 0.2 μm filtered solution of 50mM Tris-HCl, 150mM NaCl, 10% Glycerol, pH 7.5. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
| 运输条件 | 干冰运输 |
| 背景说明 | IMPAD1 protein (IMPA3，gPAPP or IMPase 3) belongs to the inositol monophosphatase family.It is found in Purkinje cells，brain stem，lung and chondrocytes.Mouse IMPAD1 gene encodes a type II transmembrane Golgi-embedded glycoprotein with 356 amino acid residues which generates a 306 amino acid residues mature protein after processing.It is expressed in embryo，and in theory may catalyze myo-inositol monophosphate to myo-inositol.Free myo-inositol is used to generate inositol phospholipid，an essential component of intracellular signaling pathways that mobilize calcium.Mouse IMPAD1 exhibits 91% sequence identity with the human homologue. |
| 来源 | Human Cells |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
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文献和实验A Femtomole-Sensitivity Mass Assay for Inositol Hexakisphosphate
sensitivities and ambiguities. Here, we describe a mass assay for InsP 6 that is based on phosphorylating InsP 6 with [32 P]-ATP to 5-(PP )InsP 5 using a recombinant Giardia InsP 6 kinase and quantification of the radiolabelled 5-[32 P](PP )InsP 5 product
Separation of Labeled Inositol Phosphate Isomers by High-Pressure Liquid Chromatography (HPLC)
Ins(1,3)P 2 , Ins(3,4)P 2 , or Ins(1,3,4,6)P 4 , respectively. Subsequent dephosphorylation of Ins(1,3)P 2 and Ins(3,4)P 2 produces Ins(l)P 1 and Ins(3)P 1 , which, along with Ins(4)P 1 , are metabolized by the inositol monophosphatase to release myo
Measurement of Second Messengers in Signal Transduction: cAMP and Inositol Phosphates
. Inositol trisphosphate, a novel second messenger in cellular signal transduction. Nature 312:315‐321. Berridge, M.J., Dawson, R.M.C., Downes, C.P., Heslop, J.P., and Irvine, R.F
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