- ￥832 - 21120
- Solarbio
- P00794
- 北京
- 2025年07月25日
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- 文献和实验
- 技术资料
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 规格：
1mg/500ug/50ug/10ug
| 规格： | 1mg | 产品价格： | ￥21120.0 |
|---|---|---|---|
| 规格： | 500ug | 产品价格： | ￥14784.0 |
| 规格： | 50ug | 产品价格： | ￥2288.0 |
| 规格： | 10ug | 产品价格： | ￥832.0 |
【本资料源自公开渠道，如需（此处）屏蔽，请联系删除】
标题:TEAD1-Mediated Trans-Differentiation of Vascular Smooth Muscle Cells into Fibroblast-Like Cells Contributes to the Stabilization and Repair of Disrupted Atherosclerotic Plaques
成员:Ming Zhai, Zhijun Lei, Yefei Shi, Jiayun Shi, Yanxi Zeng, Shiyu Gong, Weixia Jian, Jianhui Zhuang, Qing Yu, Mark W. Feinberg, Wenhui Peng
论文因子:14.3 发表期刊:Advanced Science pmid:39665254
【本资料源自公开渠道，如需（此处）屏蔽，请联系删除】
标题:Extracellular traps from activated vascular smooth muscle cells drive the progression of atherosclerosis
成员:Zhai Ming, Gong Shiyu, Luan Peipei, Shi Yefei, Kou Wenxin, Zeng Yanxi, Shi Jiayun, Yu Guanye, Hou Jiayun, Yu Qing, Jian Weixia, Zhuang Jianhui, Feinberg Mark W., Peng Wenhui
论文因子:17.694 发表期刊:Nature Communications pmid:36473863
| 基本信息 | |
| 基因名 | |
| 别名 | Oxidized Low-Density Lipoprotein Receptor 1;Ox-LDL Receptor 1;C-Type Lectin Domain Family 8 Member A;Lectin-Like Oxidized LDL Receptor 1;LOX-1;Lectin-Like oxLDL Receptor 1;hLOX-1;Lectin-Type Oxidized LDL Receptor 1;OLR1;CLEC8A;LOX1 |
| 中文名称 | Recombinant Human LOX-1/OLR1 |
| 外观(性状) | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 运输条件 | The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| 背景说明 | Oxidized Low-Density Lipoprotein Receptor 1 (Ox-LDL Receptor 1) is a secreted，single-pass type II membrane protein which belongs to the C-type lectin superfamily.Ox-LDL Receptor 1 is expressed at high levels in endothelial cells and vascular-rich organs such as placenta，lung，liver，brain，aortic intima，bone marrow，spinal cord and substantia nigra.The expression of Ox-LDL Receptor 1 is induced by inflammatory cytokines such as TNF，IFNG and IL6 by pathological conditions，such as hyperlipidemia，hypertension and diabetes mellitus.Ox-LDL Receptor 1 mediates the recognition，internalization and degradation of oxidatively modified low density lipoprotein (OxLDL) by vascular endothelial cells.Ox-LDL Receptor 1 association with oxLDL induces the activation of NF-kappa-B through an increased production of intracellular reactive oxygen and a variety of pro-atherogenic cellular responses including a reduction of nitric oxide (NO) release，monocyte adhesion and apoptosis.Ox-LDL Receptor 1 also binds to oxLDL，which acts as a receptor for the HSP70 protein involved in antigen cross-presentation to naive T-cells in dendritic cells，thereby participating in cell-mediated antigen cross-presentation.It also participates in inflammatory process，by acting as a leukocyte-adhesion molecule at the vascular interface in endotoxin-induced inflammation. |
| 来源 | Human Cells |
| 溶剂 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
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文献和实验【本资料源自公开渠道，如需（此处）屏蔽，请联系删除】
标题:TEAD1-Mediated Trans-Differentiation of Vascular Smooth Muscle Cells into Fibroblast-Like Cells Contributes to the Stabilization and Repair of Disrupted Atherosclerotic Plaques
成员:Ming Zhai, Zhijun Lei, Yefei Shi, Jiayun Shi, Yanxi Zeng, Shiyu Gong, Weixia Jian, Jianhui Zhuang, Qing Yu, Mark W. Feinberg, Wenhui Peng
论文因子:14.3 发表期刊:Advanced Science pmid:39665254
【本资料源自公开渠道，如需（此处）屏蔽，请联系删除】
标题:Extracellular traps from activated vascular smooth muscle cells drive the progression of atherosclerosis
成员:Zhai Ming, Gong Shiyu, Luan Peipei, Shi Yefei, Kou Wenxin, Zeng Yanxi, Shi Jiayun, Yu Guanye, Hou Jiayun, Yu Qing, Jian Weixia, Zhuang Jianhui, Feinberg Mark W., Peng Wenhui
论文因子:17.694 发表期刊:Nature Communications pmid:36473863
Secretion of Recombinant Human Insulin-Like Growth Factor I (IGF-I)
The development of efficient recombinant protein production processes can be a critical factor in whether or not a pharmaceutical therapeutic protein can enter human clinical trials and ultimately the marketplace. This is especially true
In this chapter we describe efficient procedures for the construction, expression and screening of comprehensive libraries of human Fab antibody fragments displayed on the surface of filamentous phage. Phagemid vectors are used for placing
我们知道，PeproTech的所有细胞因子和蛋白均为冻干粉，这使得运输非常便捷，只要常温即可。而且，细胞因子和蛋白冻干粉非常稳定，在-20℃或-80℃条件下可保存数年。冻干粉在使用前需进行溶解，然后以液体形式加到培养体系或注射入动物体内。溶解步骤非常关键，因溶解不好会导致细胞因子或蛋白的失活，这也是很多用户在实际使用中经常遇到的问题。 那么，应该如何进行正确的溶解呢？ 下面我们以Recombinant Human IL-4 (重组人IL-4，产品编号：200-04)的说明书为例
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