Recombinant Human Noggin/NOG产品图

Recombinant Human Noggin/NOG

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  • ¥764 - 14784
  • Solarbio已认证
  • 北京
  • P00644
  • 2026年08月13日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 保质期

      Upon receipt, store it immediately at -20°C or lower for long term storage. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: <br>2-8°C for 2-7 days under sterile conditions after redissolves; <br>-20°C for 1 months and -70℃ for 3 months under sterile conditions after redissolves; <br>-20°C to -70℃ for 12 months in lyophilized state.

    • 保存条件

      Upon receipt, store it immediately at -20°C or lower for long term storage. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: <br>2-8°C for 2-7 days under sterile conditions after redissolves; <br>-20°C for 1 months and -70℃ for 3 months under sterile conditions after redissolves; <br>-20°C to -70℃ for 12 months in lyophilized state.

    • 英文名

      Noggin/NOG

    • 库存

      999

    • 供应商

      北京索莱宝科技有限公司

    • 规格

      10ug/50ug/500ug/1mg

    规格:10ug产品价格:¥764.00
    规格:50ug产品价格:¥2293.00
    规格:500ug产品价格:¥10349.00
    规格:1mg产品价格:¥14784.00
    基因名Noggin/NOG
    别名Noggin; NOG
    蛋白号Q13253
    种属Human
    宿主HEK293
    产品描述Recombinant Human Noggin is produced by our Mammalian expression system and the target gene encoding Gln28-Cys232 is expressed with a Fc tag at the C-terminus.
    区间范围Gln28-Cys232
    标签信息C-Fc
    预测分子量48 KDa
    表观分子量48-96 KDa
    纯度≥95% by SDS‐PAGE.
    内毒素<0.1ng/ug(1EU/ug)as determined by LAL test.
    溶剂Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
    复溶Reconstituted protein solution can be diluted with distilled water. Always centrifuge tubes before opening. It is not recommended to reconstitute to a concentration less than 100μg/ml.
    储存条件Upon receipt, store it immediately at -20°C or lower for long term storage. Please avoid repeated freeze-thaw cycles. This product is stable after storage at:
    2-8°C for 2-7 days under sterile conditions after redissolves;
    -20°C for 1 months and -70℃ for 3 months under sterile conditions after redissolves;
    -20°C to -70℃ for 12 months in lyophilized state.
    运输条件冷冻运输
    背景说明Noggin is a secreted homodimeric glycoprotein that is an antagonist of bone morphogenetic proteins (BMPs).Mature Human Noggin contains an N-terminal acidic region, a central basic heparin-binding segment and a C-terminal cysteine-knot structure.Noggin is very highly conserved among vertebrates, such that mature human Noggin shares 99%, 99%, 98%, 97% and 89% aa sequence identity with mouse, rat bovine, equine and chicken Noggin, respectively.Secreted Noggin probably remains close to the cell surface due to its binding of heparin-containing proteoglycans.Noggin binds some BMPs such as BMP4 with high affinity and others such as BMP7 with lower affinity.It antagonizes BMP bioactivities by blocking epitopes on BMPs that are needed for binding to both type I and type II receptors.Noggin is expressed in defined areas of the adult central nervous system and peripheral tissues such as lung, skeletal muscle and skin.During culture of human embryonic stem cells (hESC) or neural stem cells under certain conditions, addition of Noggin to antagonize BMP activity may allow stem cells to proliferate while maintaining their undifferentiated state, or alternatively, to differentiate into dopaminergic neurons.
    细胞活性No activity experimental data, to be verified.
    ELISA活性No activity experimental data, to be verified.
    SPR/BLI活性No activity experimental data, to be verified.
    研究领域生物制药相关研究
    英文名称Noggin/NOG
    中文名称Noggin/NOG蛋白
    单位
    规格10ug ; 50ug ; 500ug ; 1mg

    产品问答:
    问:干粉状态-20有效期多久?
    答:您好,干粉状态-20℃环境下可以稳定保存1年。

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