P00494 Recombinant Human ROR1/Inactive tyrosine-protein kinase transmembrane receptor ROR1/Neurotrophic tyrosine kinase 细胞因子/蛋白

P00494 Recombinant Human ROR1/

Inactive tyrosine-protein kinase transmembrane receptor ROR1/Neurotrophic tyrosine kinase 细胞因子/蛋白
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  • ¥520 - 8640
  • Solarbio已认证
  • P00494
  • 北京
  • 2025年07月25日
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    • 详细信息
    • 技术资料
    • 库存

      现询

    • 供应商

      北京索莱宝科技有限公司

    • 规格

      1mg/500ug/50ug/10ug

    规格:1mg产品价格:¥8640.0
    规格:500ug产品价格:¥6048.0
    规格:50ug产品价格:¥1560.0
    规格:10ug产品价格:¥520.0
    基本信息
    基因名
    别名neurotrophic tyrosine kinase receptor-related 1;receptor tyrosine kinase-like orphan receptor 1;ROR1;tyrosine-protein kinase transmembrane receptor ROR1
    中文名称Recombinant Human ROR1/Inactive tyrosine-protein kinase transmembrane receptor ROR1/Neurotrophic tyrosine kinase
    外观(性状)Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
    纯度≥95% as determined by reducing SDS-PAGE.
    储存条件Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
    运输条件The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below.
    背景说明ROR1,also known as Neurotrophic tyrosine kinase,receptor-related 1,belongs to the ROR subfamily ofTyr protein kinase family,a protein kinase superfamily.It has very low kinase activity in vitro and is unlikelyto function as a tyrosine kinase in vivo.Human ROR1 is a type I transmembrane protein with 937 aminoacids (aa) in length.It contains a 29 aa signal sequence,a 377 aa extracellular domain (ECD),a 21 aatransmembrane segment,and a 510 aa cytoplasmic region.Human ROR1 shares 97% and 58% aa sequenceidentity with mouse ROR1 and human ROR2,respectively.ROR1 may act as a receptor for wnt ligandWNT5A which may result in the inhibition of WNT3A-mediated signaling.ROR1 expressed strongly inhuman heart,lung and kidney,but weakly in the CNS.Its Isoform Short is strongly expressed in fetal andadult CNS and in a variety of human cancers,including those originating from CNS or PNS neuroectoderm.
    来源Human Cells
    溶剂Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    内毒素Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.
    单位

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