P00484 Recombinant Human HGF R
/c-MET/Hepatocyte Growth Factor Receptor (Glu25-Thr932) 细胞因子/蛋白- ￥520 - 10080
- Solarbio
- P00484
- 北京
- 2025年07月25日
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- 文献和实验
- 技术资料
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 规格：
1mg/500ug/50ug/10ug
| 规格： | 1mg | 产品价格： | ￥10080.0 |
|---|---|---|---|
| 规格： | 500ug | 产品价格： | ￥7200.0 |
| 规格： | 50ug | 产品价格： | ￥1560.0 |
| 规格： | 10ug | 产品价格： | ￥520.0 |
| 基本信息 | |
| 基因名 | |
| 别名 | Hepatocyte growth factor receptor;HGF receptor;HGF/SF receptor;Proto-oncogene c-Met;Scatter factor receptor;SF receptor;Tyrosine-protein kinase Met;MET |
| 中文名称 | Recombinant Human HGF R/c-MET/Hepatocyte Growth Factor Receptor (Glu25-Thr932) |
| 外观(性状) | Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 运输条件 | The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| 背景说明 | Hepatocyte growth factor receptor (HGF R) is a glycosylated receptor tyrosine kinase that plays a central role in epithelial morphogenesis and cancer development.HGF R is synthesized as a single chain precursor which undergoes cotranslational proteolytic cleavage.Mature HGF R is a disulfide-linked dimer composed of a 50 kDa extracellular α chain and a 145 kDa transmembrane β chain.Proteolysis and alternate splicing generate additional forms of human HGF R which either lack of the kinase domain，consist of secreted extracellular domains，or are deficient in proteolytic separation of the α and β chains.The sema domain，which is formed by both α and β chains of HGF R，mediates both ligand binding and receptor dimerization.HGF stimulation induces HGF R downregulation via internalization and proteasomedependent degradation.Paracrine induction of epithelial cell scattering and branching tubulogenesis results from the stimulation of HGF R on undifferentiated epithelium by HGF released from neighboring mesenchymal cells. |
| 来源 | Human Cells |
| 溶剂 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
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