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P00049 Recombinant Human IGF-I

细胞因子/蛋白
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  • ¥260 - 2080
  • Solarbio已认证
  • P00049
  • 北京
  • 2025年07月25日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 库存

      现询

    • 供应商

      北京索莱宝科技有限公司

    • 规格

      1mg/500ug/50ug/10ug

    规格:1mg产品价格:¥2080.0
    规格:500ug产品价格:¥1456.0
    规格:50ug产品价格:¥468.0
    规格:10ug产品价格:¥260.0

    Recombinant Human Insulin-like Growth Factor I is produced by our E.coli expression system and the target gene encoding Gly49-Ala118 is expressed.

    【本资料源自公开渠道,如需(此处)屏蔽,请联系删除】

    标题:Cannabidiol Enhances Microglial Beta-Amyloid Peptide Phagocytosis and Clearance via Vanilloid Family Type 2 Channel Activation

    成员:Shaobin Yang, Yaqin Du, Xiaoqian Zhao, Qi Tang, Wei Su, Yuemeng Hu, Peng Yu

    论文因子:6.208 发表期刊:INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES pmid:35628181

    【本资料源自公开渠道,如需(此处)屏蔽,请联系删除】

    标题:Antiplatelet drug ticagrelor suppresses triple negative breast cancer metastasis by targeting PI3K

    成员:Rong Wang, Shutao Jia, Hongyan Chen, Kaitao Luo, Limei Zhang, Yan Song, Chen Qing, Dandan Liu, Hongyu Zhou

    论文因子:5.3 发表期刊:BIOCHEMICAL PHARMACOLOGY pmid:38969297

    【本资料源自公开渠道,如需(此处)屏蔽,请联系删除】

    标题:IGF-1 Combined with OPN Promotes Neuronal Axon Growth in Vitro Through the IGF-1R/Akt/mTOR Signaling Pathway in Lipid Rafts

    成员:Zhao Qin, Su Hong, Jiang Wei, Luo Haodong, Pan Lu, Liu Yuan, Yang Ce, Yin Ying, Yu Lehua, Tan Botao

    论文因子:4.4 发表期刊:NEUROCHEMICAL RESEARCH pmid:37395917

    基本信息
    基因名
    别名Insulin-Like Growth Factor I;IGF-I;Mechano Growth Factor;MGF;Somatomedin-C;IGF1;IBP1
    外观(性状)Lyophilized from a 0.2 μm filtered solution of 300mM NaAc, pH 6.5.
    纯度≥95% as determined by reducing SDS-PAGE.
    储存条件Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
    运输条件The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below.
    背景说明Insulin-like growth factor I (IGF1) belongs to the family of insulin-like growth factors that are structurally homologous to proinsulin.Mature IGFs are generated by proteolytic processing of inactive precursor proteins,which contains the N- and C-terminal propeptide regions.Mature human IGF-I consisting of 70 amino acids has 94% identity with mouse IGF-I and exhibits cross-species activity.IGF-1 binds IGF-IR,IGF-IIR,and the insulin receptor and plays a key role in cell cycle progression,cell proliferation and tumor progression.IGF-1 expression is regulated by growth hormone.R3 IGF-1 is an 83 amino acid analog of IGF-1 comprising the complete human IGF-1 sequence with the substitution of an Arg (R) for the Glu(E) at position three,hence R3,and a 13 amino acid extension peptide at the N terminus.R3 IGF-1 has been produced with the purpose of increasing biological activity.R3 IGF-1 is significantly more potent than human IGF-I in vitro.
    来源E.coli
    溶剂Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
    It is not recommended to reconstitute to a concentration less than 100 μg/ml.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    内毒素Less than 0.05 ng/ug(0.5 IEU/ug)as determined by LAL test.
    单位

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    该产品被引用文献

    【本资料源自公开渠道,如需(此处)屏蔽,请联系删除】

    标题:Cannabidiol Enhances Microglial Beta-Amyloid Peptide Phagocytosis and Clearance via Vanilloid Family Type 2 Channel Activation

    成员:Shaobin Yang, Yaqin Du, Xiaoqian Zhao, Qi Tang, Wei Su, Yuemeng Hu, Peng Yu

    论文因子:6.208 发表期刊:INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES pmid:35628181

    【本资料源自公开渠道,如需(此处)屏蔽,请联系删除】

    标题:Antiplatelet drug ticagrelor suppresses triple negative breast cancer metastasis by targeting PI3K

    成员:Rong Wang, Shutao Jia, Hongyan Chen, Kaitao Luo, Limei Zhang, Yan Song, Chen Qing, Dandan Liu, Hongyu Zhou

    论文因子:5.3 发表期刊:BIOCHEMICAL PHARMACOLOGY pmid:38969297

    【本资料源自公开渠道,如需(此处)屏蔽,请联系删除】

    标题:IGF-1 Combined with OPN Promotes Neuronal Axon Growth in Vitro Through the IGF-1R/Akt/mTOR Signaling Pathway in Lipid Rafts

    成员:Zhao Qin, Su Hong, Jiang Wei, Luo Haodong, Pan Lu, Liu Yuan, Yang Ce, Yin Ying, Yu Lehua, Tan Botao

    论文因子:4.4 发表期刊:NEUROCHEMICAL RESEARCH pmid:37395917

    相关实验
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      -like growth factor I (IGF-I) production process in which P. pastoris is used as the recombinant host strain is discussed in this chapter.

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      In this chapter we describe efficient procedures for the construction, expression and screening of comprehensive libraries of human Fab antibody fragments displayed on the surface of filamentous phage. Phagemid vectors are used for placing

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    P00049 Recombinant Human IGF-I 细胞因子/蛋白
    ¥260 - 2080